SCHEMBL8153202

SCHEMBL8153202

C[C@H]1CC[C@H](c2ccc(/C=C/C(=O)O)cc2)CC1

nearest known ligand 0.51

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ESR2 Q92731 2/20 0.51
ESR1 P03372 5/20 0.49
HCAR2 Q8TDS4 2/20 0.49
CA12 O43570 2/20 0.49
AKR1B10 O60218 2/20 0.49
CA1 P00915 2/20 0.49
CA2 P00918 2/20 0.49
CA3 P07451 2/20 0.49
AKR1B1 P15121 2/20 0.49
CA4 P22748 2/20 0.49
CA6 P23280 2/20 0.49
DPP4 P27487 2/20 0.49
CA5A P35218 2/20 0.49
CA7 P43166 2/20 0.49
CA9 Q16790 2/20 0.49
CA14 Q9ULX7 2/20 0.49
CA5B Q9Y2D0 2/20 0.49
PKM P14618 1/20 0.49
TYR P14679 1/20 0.49
KDM4E B2RXH2 4/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8153204 1.00 ESR2 (0.51) ESR2ESR1HCAR2CA12AKR1B10
SCHEMBL1088808 1.00 ESR2 (0.51) ESR2ESR1HCAR2CA12AKR1B10
SCHEMBL8153206 1.00 ESR2 (0.51) ESR2ESR1HCAR2CA12AKR1B10
SCHEMBL4002821 0.92 ESR1 (0.57) ESR2ESR1HCAR2CA12AKR1B10
SCHEMBL4002818 0.92 ESR1 (0.57) ESR2ESR1HCAR2CA12AKR1B10
SCHEMBL15043515 0.87 ESR2 (0.51) ESR2ESR1HDAC3HDAC1HDAC2
SCHEMBL8148920 0.86 ESR2 (0.50) ESR2ESR1HDAC3HDAC1HDAC2
SCHEMBL8148925 0.86 ESR2 (0.50) ESR2ESR1HDAC3HDAC1HDAC2
SCHEMBL8148927 0.86 ESR2 (0.50) ESR2ESR1HDAC3HDAC1HDAC2
SCHEMBL8148923 0.86 ESR2 (0.50) ESR2ESR1HDAC3HDAC1HDAC2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-RE36625-E Linear and cyclic polymers or oligomers having a photoreactive ethene group ROLIC AG (CH) 2000-03-21 US disclosed
US-5539074-A LIQUID CRYSTAL POLYMERS ON SILICA FOR LIGHT SENSITIVE ELEMENTS HOFFMANN-LA ROCHE INC. (US) 1996-07-23 US disclosed