SCHEMBL8153283

SCHEMBL8153283

C[C@H]1CC[C@H](CCc2ccc(F)c(F)c2)CC1

nearest known ligand 0.44

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
SLC6A2 P23975 1/20 0.42
SLC6A4 P31645 1/20 0.42
SLC6A3 Q01959 1/20 0.42
NPC1 O15118 1/20 0.38
ALDH1A1 P00352 2/20 0.37
HTT P42858 1/20 0.37
CNR1 P21554 1/20 0.36
MAOB P27338 2/20 0.36
MAOA P21397 1/20 0.36
DAO P14920 1/20 0.36
GPR84 Q9NQS5 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9979951 1.00 SLC6A2 (0.42) SLC6A2SLC6A4SLC6A3NPC1ALDH1A1
SCHEMBL13171736 0.95 SLC6A2 (0.40) SLC6A2SLC6A4SLC6A3NPC1ALDH1A1
SCHEMBL13433711 0.95 SLC6A2 (0.40) SLC6A2SLC6A4SLC6A3NPC1ALDH1A1
SCHEMBL9331600 0.91 SLC6A2 (0.37) SLC6A2SLC6A4SLC6A3NPC1ALDH1A1
SCHEMBL9331612 0.91 SLC6A2 (0.37) SLC6A2SLC6A4SLC6A3NPC1ALDH1A1
SCHEMBL9331594 0.91 SLC6A2 (0.37) SLC6A2SLC6A4SLC6A3NPC1ALDH1A1
SCHEMBL9331607 0.91 SLC6A2 (0.37) SLC6A2SLC6A4SLC6A3NPC1ALDH1A1
SCHEMBL9331646 0.88 SLC6A2 (0.35) SLC6A2SLC6A4SLC6A3NPC1ALDH1A1
SCHEMBL9331651 0.88 SLC6A2 (0.35) SLC6A2SLC6A4SLC6A3NPC1ALDH1A1
SCHEMBL9331629 0.88 SLC6A2 (0.35) SLC6A2SLC6A4SLC6A3NPC1ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-RE36849-E 2-(4-(ALK(EN)YL, ALKOXY, ALKANOYL)-4'-BICYCLOHEXYL)-1-(2,3-(HALO OR NITRILE),4-HALOPHENYL)ETHANE COMPOUNDS; ELECTROOPTICAL DISPLAY WITH MULTIPLEX OPERATION COMPRISING A LIQUID CRYSTAL MIXTURE AS DIELECTRIC MERCK PATENT GMBH (DE) 2000-09-05 US claimed
US-RE36849-E 2-(4-(ALK(EN)YL, ALKOXY, ALKANOYL)-4'-BICYCLOHEXYL)-1-(2,3-(HALO OR NITRILE),4-HALOPHENYL)ETHANE COMPOUNDS; ELECTROOPTICAL DISPLAY WITH MULTIPLEX OPERATION COMPRISING A LIQUID CRYSTAL MIXTURE AS DIELECTRIC MERCK PATENT GMBH (DE) 2000-09-05 US disclosed
US-4710315-A USE WITH MULTIPLEXIBLE DISPLAYS HAVING HIGH DENSITY IMAGES MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) 1987-12-01 US disclosed