SCHEMBL8153384

SCHEMBL8153384

O=C(C1CCN[C@@H]1C(O)=S)[C@@H]1CCCN1C(=O)CC1Cc2ccccc2C1

nearest known ligand 0.56

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
PREP P48147 20/20 0.56

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9048984 0.95 PREP (0.58) PREP
SCHEMBL9047793 0.95 PREP (0.58) PREP
SCHEMBL9050498 0.90 PREP (0.44) PREP
SCHEMBL9049455 0.89 PREP (0.45) PREP
SCHEMBL9050181 0.88 PREP (0.47) PREP
SCHEMBL9048117 0.88 PREP (0.42) PREP
SCHEMBL9046377 0.88 PREP (0.47) PREP
SCHEMBL9050209 0.86 PREP (0.46) PREP
SCHEMBL9049198 0.86 PREP (0.46) PREP
SCHEMBL9049902 0.82 F2 (0.48) PREP

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6017929-A Cholinesterase activator ZERIA PHARMACEUTICAL CO., LTD. (JP) 2000-01-25 US disclosed
EP-0754454-A1 CHOLINESTERASE ACTIVATOR ZERIA PHARMACEUTICAL CO., LTD. (JP) 1997-01-22 EP disclosed
EP-0536399-B1 NOVEL ARYLALKANOYLAMINE DERIVATIVE AND DRUG CONTAINING THE SAME ZERIA PHARM CO LTD (JP) 1996-01-24 EP disclosed
US-5407950-A Brain disorders, senile dementia ZERIA PHARMACEUTICAL CO., LTD. (JP) 1995-04-18 US disclosed
EP-0536399-A1 NOVEL ARYLALKANOYLAMINE DERIVATIVE AND DRUG CONTAINING THE SAME ZERIA PHARMACEUTICAL CO., LTD. (JP) 1993-04-14 EP disclosed