Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.57 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.57 |
| ▸ | CES1 | P23141 | 7/20 | 0.52 |
| ▸ | FDPS | P14324 | 1/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.45 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.45 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.45 |
| ▸ | CES2 | O00748 | 1/20 | 0.44 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.44 |
| ▸ | FAAH | O00519 | 3/20 | 0.43 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.42 |
| ▸ | CPA1 | P15085 | 1/20 | 0.42 |
| ▸ | CHRM1 | P11229 | 3/20 | 0.41 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.41 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.41 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.41 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.41 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.41 |
| ▸ | ARG1 | P05089 | 1/20 | 0.41 |
| ▸ | ARG2 | P78540 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Magnesium SCHEMBL31592027 | 0.98 | SMN1; SMN2 (0.55) | SMN1; SMN2HIF1ACES1FDPSCYP1A2 | |
| SCHEMBL5235928 | 0.82 | SMN1; SMN2 (0.57) | SMN1; SMN2HIF1ACES1FDPSCYP1A2 | |
| SCHEMBL25267515 | 0.81 | PPARG (0.45) | SMN1; SMN2CYP1A2CYP2C9CYP2C19SLC6A2 | |
| SCHEMBL8164278 | 0.81 | CES1 (0.47) | SMN1; SMN2HIF1ACES1FDPSCYP1A2 | |
| SCHEMBL27534990 | 0.80 | SMN1; SMN2 (0.55) | SMN1; SMN2HIF1ACES1FDPSCYP1A2 | |
| SCHEMBL1272429 | 0.78 | SMN1; SMN2 (0.64) | SMN1; SMN2HIF1ACES1FDPSCYP1A2 | |
| SCHEMBL6472726 | 0.78 | SMN1; SMN2 (0.53) | SMN1; SMN2HIF1ACES1FDPSCYP1A2 | |
| SCHEMBL10908764 | 0.78 | SMN1; SMN2 (0.53) | SMN1; SMN2HIF1ACES1FDPSCYP1A2 | |
| SCHEMBL1272430 | 0.78 | SMN1; SMN2 (0.64) | SMN1; SMN2HIF1ACES1FDPSCYP1A2 | |
| SCHEMBL2032323 | 0.78 | SMN1; SMN2 (0.64) | SMN1; SMN2HIF1ACES1FDPSCYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-2000256272-A | REAGENT AND METHOD FOR STEREOSPECIFIC FLUOROMETHYLATION | PROTOTEK INC | 2000-09-19 | — | — | JP | disclosed |
| EP-0442754-B1 | Reagents and methods for stereospecific fluoromethylation | PROTOTEK INC (US) | 1995-12-27 | — | — | EP | disclosed |
| US-5344939-A | Esterification | PROTOTEK, INC. (US) | 1994-09-06 | — | — | US | disclosed |
| US-5210272-A | Using a magnesium fluoromalonate to fluoromethylate a carboxylic acid | PROTOTEK, INC. (US) | 1993-05-11 | — | — | US | disclosed |
| US-5101068-A | Monofluoromethylation of organic compounds, reaction with amino acids | PROTOTEK INC. (US) | 1992-03-31 | — | — | US | disclosed |
| EP-0442754-A2 | Reagents and methods for stereospecific fluoromethylation | PROTOTEK, INC., (US) | 1991-08-21 | — | — | EP | disclosed |