Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MCOLN2 | Q8IZK6 | 8/20 | 0.50 |
| ▸ | MCOLN1 | Q9GZU1 | 8/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | MCOLN3 | Q8TDD5 | 6/20 | 0.35 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | SLC18A3 | Q16572 | 1/20 | 0.32 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7343637 | 0.87 | TDP1 (0.41) | MCOLN2MCOLN1KMT2ATDP1SIGMAR1 | |
| SCHEMBL2441220 | 0.87 | TDP1 (0.41) | MCOLN2MCOLN1KMT2ATDP1SIGMAR1 | |
| SCHEMBL2441202 | 0.87 | TDP1 (0.41) | MCOLN2MCOLN1KMT2ATDP1SIGMAR1 | |
| SCHEMBL8762939 | 0.87 | TDP1 (0.41) | MCOLN2MCOLN1KMT2ATDP1SIGMAR1 | |
| SCHEMBL8761967 | 0.85 | CHRNA7 (0.41) | MCOLN2MCOLN1KMT2ATDP1SLC18A3 | |
| SCHEMBL10366438 | 0.85 | CHRNA7 (0.41) | MCOLN2MCOLN1KMT2ATDP1SLC18A3 | |
| SCHEMBL10366437 | 0.85 | CHRNA7 (0.41) | MCOLN2MCOLN1KMT2ATDP1SLC18A3 | |
| SCHEMBL11465447 | 0.85 | CHRNA7 (0.41) | MCOLN2MCOLN1KMT2ATDP1SLC18A3 | |
| SCHEMBL8761961 | 0.85 | CHRNA7 (0.41) | MCOLN2MCOLN1KMT2ATDP1SLC18A3 | |
| SCHEMBL10366436 | 0.85 | CHRNA7 (0.41) | MCOLN2MCOLN1KMT2ATDP1SLC18A3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1269719-A | Aroylpiperazines for modulating sexual activity | NORTRAN PHARMACEUTICALS INC (CA) | 2000-10-11 | — | — | CN | disclosed |
| EP-1001776-A1 | AROYLPIPERAZINES FOR MODULATING SEXUAL ACTIVITY | Nortran Pharmaceuticals Inc. (CA) | 2000-05-24 | — | — | EP | disclosed |
| WO-1999002159-A1 | AROYLPIPERAZINES FOR MODULATING SEXUAL ACTIVITY | NORTRAN PHARMACEUTICALS INC. (CA) | 1999-01-21 | — | — | WO | disclosed |