Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ZAP70 | P43403 | 9/20 | 0.54 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.54 |
| ▸ | EGFR | P00533 | 1/20 | 0.54 |
| ▸ | PRKCG | P05129 | 1/20 | 0.54 |
| ▸ | PRKCB | P05771 | 1/20 | 0.54 |
| ▸ | LCK | P06239 | 1/20 | 0.54 |
| ▸ | PRKCA | P17252 | 1/20 | 0.54 |
| ▸ | PRKCH | P24723 | 1/20 | 0.54 |
| ▸ | PRKCI | P41743 | 1/20 | 0.54 |
| ▸ | PRKCE | Q02156 | 1/20 | 0.54 |
| ▸ | PRKCQ | Q04759 | 1/20 | 0.54 |
| ▸ | PRKCZ | Q05513 | 1/20 | 0.54 |
| ▸ | PRKCD | Q05655 | 1/20 | 0.54 |
| ▸ | PRKD1 | Q15139 | 1/20 | 0.54 |
| ▸ | MYLK4 | Q86YV6 | 2/20 | 0.49 |
| ▸ | STK17A | Q9UEE5 | 2/20 | 0.49 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.49 |
| ▸ | TBK1 | Q9UHD2 | 1/20 | 0.49 |
| ▸ | EPHB4 | P54760 | 1/20 | 0.45 |
| ▸ | MAP3K11 | Q16584 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8446973 | 0.88 | ZAP70 (0.55) | ZAP70PRKD3EGFRPRKCGPRKCB | |
| SCHEMBL6957620 | 0.86 | ZAP70 (0.58) | ZAP70PRKD3EGFRPRKCGPRKCB | |
| SCHEMBL8138939 | 0.81 | ZAP70 (0.64) | ZAP70PRKD3EGFRPRKCGPRKCB | |
| SCHEMBL8146572 | 0.81 | HDAC1 (0.48) | ZAP70PRKD3EGFRPRKCGPRKCB | |
| SCHEMBL8152774 | 0.80 | ZAP70 (0.62) | ZAP70PRKD3EGFRPRKCGPRKCB | |
| SCHEMBL6952360 | 0.79 | ZAP70 (0.68) | ZAP70PRKD3EGFRPRKCGPRKCB | |
| SCHEMBL7081451 | 0.79 | ZAP70 (0.74) | ZAP70PRKD3EGFRPRKCGPRKCB | |
| SCHEMBL8146573 | 0.77 | ZAP70 (0.56) | ZAP70PRKD3EGFRPRKCGPRKCB | |
| SCHEMBL6957800 | 0.77 | ZAP70 (0.66) | ZAP70PRKD3EGFRPRKCGPRKCB | |
| Dimethylamine SCHEMBL7267011 | 0.76 | ZAP70 (0.68) | ZAP70PRKD3EGFRPRKCGPRKCB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6093716-A | Substituted 2-pyrimidineamines and processes for their preparation | CELLTECH THERAPEUTICS, LIMITED (GB) | 2000-07-25 | — | — | US | disclosed |