Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.54 |
| ▸ | THRB | P10828 | 1/20 | 0.54 |
| ▸ | HTT | P42858 | 1/20 | 0.54 |
| ▸ | MAPT | P10636 | 1/20 | 0.54 |
| ▸ | TSHR | P16473 | 4/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | FAAH | O00519 | 2/20 | 0.35 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.35 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11137622 | 0.98 | MEN1 (0.50) | MEN1KMT2ATHRBHTTMAPT | |
| SCHEMBL8730359 | 0.98 | MEN1 (0.50) | MEN1KMT2ATHRBHTTMAPT | |
| SCHEMBL26068215 | 0.91 | MEN1 (0.54) | MEN1KMT2ATHRBHTTMAPT | |
| SCHEMBL8324854 | 0.91 | MEN1 (0.52) | MEN1KMT2ATHRBHTTMAPT | |
| SCHEMBL28157521 | 0.91 | MEN1 (0.52) | MEN1KMT2ATHRBHTTMAPT | |
| SCHEMBL8390299 | 0.91 | MEN1 (0.52) | MEN1KMT2ATHRBHTTMAPT | |
| SCHEMBL16657344 | 0.91 | MEN1 (0.52) | MEN1KMT2ATHRBHTTMAPT | |
| SCHEMBL7520620 | 0.89 | GAA (0.46) | MEN1KMT2ATHRBHTTMAPT | |
| SCHEMBL2320452 | 0.89 | — | — | |
| Triethylene Glycol SCHEMBL10440097 | 0.89 | MEN1 (0.55) | MEN1KMT2ATHRBHTTMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0988292-A2 | PIPERAZINE DERIVATIVES AND THEIR USE AS ANTI-INFLAMMATORY AGENTS | SCHERING AKTIENGESELLSCHAFT (DE) | 2000-03-29 | — | — | EP | claimed |
| WO-1998056771-A2 | PIPERAZINE DERIVATIVES AND THEIR USE AS ANTI-INFLAMMATORY AGENTS | SCHERING AKTIENGESELLSCHAFT (DE) | 1998-12-17 | — | — | WO | claimed |
| WO-1997024428-A1 | DETERGENT COMPOSITIONS COMPRISING PSYCHROPHILIC/PSYCHROTROPHIC ENZYMES | THE PROCTER & GAMBLE COMPANY (US) | 1997-07-10 | — | — | WO | disclosed |