Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM5C | P41229 | 12/20 | 0.61 |
| ▸ | KDM2A | Q9Y2K7 | 8/20 | 0.61 |
| ▸ | KDM3A | Q9Y4C1 | 8/20 | 0.61 |
| ▸ | KDM4A | O75164 | 8/20 | 0.61 |
| ▸ | KDM4C | Q9H3R0 | 7/20 | 0.61 |
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.61 |
| ▸ | KDM6B | O15054 | 4/20 | 0.52 |
| ▸ | P4HA1 | P13674 | 1/20 | 0.50 |
| ▸ | KDM4B | O94953 | 5/20 | 0.47 |
| ▸ | KDM5B | Q9UGL1 | 5/20 | 0.47 |
| ▸ | JMJD6 | Q6NYC1 | 2/20 | 0.46 |
| ▸ | P4HTM | Q9NXG6 | 1/20 | 0.44 |
| ▸ | CA2 | P00918 | 1/20 | 0.43 |
| ▸ | CA4 | P22748 | 1/20 | 0.43 |
| ▸ | KMO | O15229 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28374030 | 0.98 | KDM5C (0.63) | KDM5CKDM2AKDM3AKDM4AKDM4C | |
| SCHEMBL15401893 | 0.96 | KDM5C (0.61) | KDM5CKDM2AKDM3AKDM4AKDM4C | |
| SCHEMBL4848322 | 0.96 | KDM5C (0.61) | KDM5CKDM2AKDM3AKDM4AKDM4C | |
| SCHEMBL528024 | 0.96 | KDM5C (0.61) | KDM5CKDM2AKDM3AKDM4AKDM4C | |
| Lithium Ion SCHEMBL25269674 | 0.96 | KDM5C (0.61) | KDM5CKDM2AKDM3AKDM4AKDM4C | |
| SCHEMBL25219643 | 0.96 | KDM5C (0.61) | KDM5CKDM2AKDM3AKDM4AKDM4C | |
| Potassium Ion SCHEMBL25270943 | 0.96 | KDM5C (0.66) | KDM5CKDM2AKDM3AKDM4AKDM4C | |
| SCHEMBL25222959 | 0.96 | KDM5C (0.61) | KDM5CKDM2AKDM3AKDM4AKDM4C | |
| SCHEMBL25273098 | 0.96 | KDM5C (0.61) | KDM5CKDM2AKDM3AKDM4AKDM4C | |
| SCHEMBL2187195 | 0.96 | KDM5C (0.61) | KDM5CKDM2AKDM3AKDM4AKDM4C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6140138-A | RAPID, EFFICIENT, AND SENSITIVE DETECTION USING A CHEMICAL MOIETY WHICH IS A BIOLOGICAL MATERIAL ATTACHED TO A COMPOUND WHICH CAN BE ACTIVATED REPEATEDLY TO CHEMILUMINESCE IF EXPOSED TO ELECTROCHEMICAL ENERGY; REPORTER MOLECULES | IGEN INTERNATIONAL INC. (US) | 2000-10-31 | — | — | US | disclosed |
| US-5731147-A | INDUCING CHEMICAL MOIETY TO ELECTROLUMINESCENCE WHICH IS DETECTED; DIAGNOSIS/MEDICAL | IGEN INTERNATIONAL, INC. (US) | 1998-03-24 | — | — | US | disclosed |
| US-5714089-A | RUTHENIUM- OR OSMIUM-CONTAINING ORGANOMETALLIC COMPLEX; QUANTITATIVE ANALYSIS, MEDICAL DIAGNOSIS, SENSITIVITY, EFFICIENCY | IGEN INTERNATIONAL, INC. (US) | 1998-02-03 | — | — | US | disclosed |
| US-5527710-A | MIXING REACTANT, LUMINOPHORE, BIOMOLECULAR REACTION PARTNER, EXPOSING TO SERIES OF ELECTRICAL PULSES AT PRESELECTED POTENTIAL AND INTERVALS, MEASURING ELECTROCHEMILUMINESCENCE, REPEATING WITH REACTED MIXTURE, AND WITHOUT REACTION PARTNER | IGEN, INC. (US) | 1996-06-18 | — | — | US | disclosed |
| US-5310687-A | Ruthenium and osmium compounds, analyzing biological materials | IGEN, INC. (US) | 1994-05-10 | — | — | US | disclosed |