SCHEMBL8155016

SCHEMBL8155016

Cc1ccc2cc(Cl)c(F)cc2c1

nearest known ligand 0.54

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP2A6 P11509 4/20 0.54
CYP1A2 P05177 4/20 0.54
TDP1 Q9NUW8 1/20 0.46
APP P05067 1/20 0.38
LMNA P02545 3/20 0.38
KMT2A Q03164 2/20 0.38
MEN1 O00255 1/20 0.38
NPC1 O15118 1/20 0.38
HTT P42858 1/20 0.38
RAB9A P51151 1/20 0.38
SMN1; SMN2 Q16637 1/20 0.38
RAPGEF4 Q8WZA2 2/20 0.36
HTR2A P28223 3/20 0.35
HTR2C P28335 3/20 0.35
PTPN1 P18031 1/20 0.35
CYP3A4 P08684 1/20 0.35
CYP2C9 P11712 1/20 0.35
HTR2B P41595 1/20 0.35
NCK1 P16333 1/20 0.34
BACE1 P56817 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8148720 1.00 CYP2A6 (0.54) CYP2A6CYP1A2TDP1APPLMNA
SCHEMBL8153333 0.84 CYP1A2 (0.68) CYP2A6CYP1A2TDP1LMNAPTPN1
SCHEMBL8141031 0.84 CYP1A2 (0.68) CYP2A6CYP1A2TDP1LMNAKMT2A
SCHEMBL21507502 0.78 CYP1A2 (0.59) CYP2A6CYP1A2TDP1LMNAKMT2A
SCHEMBL12227986 0.78 CYP1A2 (0.59) CYP2A6CYP1A2TDP1LMNAPTPN1
SCHEMBL20802473 0.78 CYP1A2 (0.59) CYP2A6CYP1A2TDP1LMNAKMT2A
SCHEMBL21507506 0.78 CYP1A2 (0.59) CYP2A6CYP1A2TDP1LMNAPTPN1
SCHEMBL8149748 0.75 CYP2A6 (0.54) CYP2A6CYP1A2TDP1LMNAPTPN1
SCHEMBL8148709 0.75 CYP2A6 (0.54) CYP2A6CYP1A2TDP1LMNAPTPN1
SCHEMBL170493 0.75

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7198827-B1 Nematic liquid crystal composition and liquid crystal display device using the same DAINIPPON INK AND CHEMICALS, INC. (JP) 2007-04-03 US disclosed
US-7198827-B1 Nematic liquid crystal composition and liquid crystal display device using the same DAINIPPON INK AND CHEMICALS, INC. (JP) 2007-04-03 US disclosed
US-20040116399-A1 Inhibitors of factor Xa MILLENNIUM PHARMACEUTICALS, INC. 2004-06-17 US disclosed
US-20040116399-A1 Inhibitors of factor Xa MILLENNIUM PHARMACEUTICALS, INC. 2004-06-17 US disclosed