Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ANPEP | P15144 | 1/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.55 |
| ▸ | MME | P08473 | 1/20 | 0.51 |
| ▸ | MEN1 | O00255 | 3/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.50 |
| ▸ | MAPT | P10636 | 1/20 | 0.50 |
| ▸ | SLC1A2 | P43004 | 1/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.50 |
| ▸ | GAA | P10253 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4746610 | 1.00 | ANPEP (0.57) | ANPEPKMT2AMMEMEN1ALDH1A1 | |
| SCHEMBL7432155 | 1.00 | ANPEP (0.57) | ANPEPKMT2AMMEMEN1ALDH1A1 | |
| Hydrochloric Acid SCHEMBL8617723 | 0.98 | ANPEP (0.56) | ANPEPKMT2AMMEMEN1ALDH1A1 | |
| Hydrochloric Acid SCHEMBL8617714 | 0.98 | ANPEP (0.56) | ANPEPKMT2AMMEMEN1ALDH1A1 | |
| Glycine SCHEMBL29077112 | 0.94 | ANPEP (0.52) | ANPEPKMT2AMMEMEN1ALDH1A1 | |
| Glycerin SCHEMBL29077115 | 0.92 | ANPEP (0.50) | ANPEPKMT2AMMEMEN1ALDH1A1 | |
| Hydrochloric Acid SCHEMBL8617140 | 0.90 | BACE1 (0.55) | ANPEPKMT2AMMEMEN1ALDH1A1 | |
| Hydrochloric Acid SCHEMBL8617134 | 0.90 | BACE1 (0.55) | ANPEPKMT2AMMEMEN1ALDH1A1 | |
| SCHEMBL3668459 | 0.86 | CA1 (0.47) | ANPEPKMT2AMMEMEN1 | |
| SCHEMBL4747242 | 0.86 | MEN1 (0.56) | ANPEPKMT2AMEN1ALDH1A1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008119772-A1 | AMIDE DERIVATIVES AS INHIBITORS OF ASPARTYL PROTEASES | MEDIVIR AB (SE) | 2008-10-09 | — | — | WO | disclosed |
| EP-0564924-B1 | 2-Oxoethyl derivatives as immunosuppressants | BAYER AG (US) | 1998-09-09 | — | — | EP | disclosed |
| EP-0610743-B1 | Aminomethylene-peptides as immunosuppressants | BAYER AG (US) | 1998-09-09 | — | — | EP | disclosed |
| EP-0838471-A1 | PEPTIDE DERIVATIVES AND ANGIOTENSIN IV RECEPTOR AGONIST | SAGAMI CHEMICAL RESEARCH CENTER (JP) | 1998-04-29 | — | — | EP | disclosed |
| US-5686424-A | FOR TREATING INFLAMMATION | MILES INC. (US) | 1997-11-11 | — | — | US | disclosed |
| US-5385918-A | Aminomethylene-peptides as immunosuppressants | MILES INC. (US) | 1995-01-31 | — | — | US | disclosed |
| EP-0610743-A1 | Novel aminomethylene-peptides as immunosuppressants | Bayer Corporation (US) | 1994-08-17 | — | — | EP | disclosed |
| EP-0564924-A2 | 2-Oxoethyl derivatives as immunosuppressants | Bayer Corporation (US) | 1993-10-13 | — | — | EP | disclosed |