Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FNTA | P49354 | 20/20 | 0.59 |
| ▸ | FNTB | P49356 | 19/20 | 0.59 |
| ▸ | PGGT1B | P53609 | 4/20 | 0.53 |
| ▸ | NRAS | P01111 | 1/20 | 0.44 |
| ▸ | HRAS | P01112 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8155158 | 1.00 | FNTA (0.59) | FNTAFNTBPGGT1BNRASHRAS | |
| Hydrochloric Acid SCHEMBL8141554 | 0.99 | FNTA (0.59) | FNTAFNTBPGGT1BNRASHRAS | |
| SCHEMBL8154508 | 0.89 | FNTA (0.70) | FNTAFNTBPGGT1BNRASHRAS | |
| SCHEMBL8154515 | 0.89 | FNTA (0.70) | FNTAFNTBPGGT1BNRASHRAS | |
| Hydrochloric Acid SCHEMBL8147140 | 0.88 | FNTA (0.69) | FNTAFNTBPGGT1BNRASHRAS | |
| SCHEMBL8147166 | 0.88 | FNTA (0.50) | FNTAFNTBPGGT1BNRASHRAS | |
| SCHEMBL3684991 | 0.84 | FNTA (0.82) | FNTAFNTBPGGT1BNRASHRAS | |
| SCHEMBL3501295 | 0.84 | FNTA (0.82) | FNTAFNTBPGGT1BNRASHRAS | |
| Hydrochloric Acid SCHEMBL8447666 | 0.84 | FNTA (0.81) | FNTAFNTBPGGT1BNRASHRAS | |
| SCHEMBL8006490 | 0.79 | FNTA (0.86) | FNTAFNTBPGGT1BNRASHRAS |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6060038-A | Radiolabeled farnesyl-protein transferase inhibitors | MERCK & CO., INC. (US) | 2000-05-09 | — | — | US | disclosed |