Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.46 |
| ▸ | RXFP1 | Q9HBX9 | 4/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | PRNP | P04156 | 1/20 | 0.46 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | POLB | P06746 | 2/20 | 0.42 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.42 |
| ▸ | NQO2 | P16083 | 4/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | THRB | P10828 | 1/20 | 0.38 |
| ▸ | NCEH1 | Q6PIU2 | 1/20 | 0.38 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.37 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.37 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8147509 | 1.00 | MAPT (0.46) | MAPTRXFP1NPSR1ALDH1A1PRNP | |
| SCHEMBL8502354 | 0.88 | CYP2A6 (0.50) | MAPTRXFP1NPSR1ALDH1A1PRNP | |
| SCHEMBL8404534 | 0.81 | CYP2A6 (0.56) | MAPTALDH1A1CYP2A6KDM4EMEN1 | |
| SCHEMBL9381604 | 0.81 | CA12 (0.52) | RXFP1PRNPCYP2A6KDM4EMEN1 | |
| SCHEMBL17912844 | 0.80 | CYP1A2 (0.54) | MAPTALDH1A1CYP2A6KDM4EMEN1 | |
| SCHEMBL17912825 | 0.80 | CYP1A2 (0.54) | MAPTALDH1A1CYP2A6KDM4EMEN1 | |
| SCHEMBL21507510 | 0.80 | CYP2A6 (0.54) | MAPTALDH1A1CYP2A6KDM4EMEN1 | |
| SCHEMBL15317150 | 0.80 | CYP2A6 (0.54) | MAPTALDH1A1CYP2A6KDM4EMEN1 | |
| SCHEMBL359387 | 0.79 | POLB (0.52) | MAPTNPSR1ALDH1A1CYP2A6KDM4E | |
| SCHEMBL15317151 | 0.79 | PDE4A (0.44) | MAPTRXFP1NPSR1ALDH1A1PRNP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040116399-A1 | Inhibitors of factor Xa | MILLENNIUM PHARMACEUTICALS, INC. | 2004-06-17 | — | — | US | disclosed |
| US-20040116399-A1 | Inhibitors of factor Xa | MILLENNIUM PHARMACEUTICALS, INC. | 2004-06-17 | — | — | US | disclosed |