Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FNTA | P49354 | 13/20 | 0.39 |
| ▸ | FNTB | P49356 | 11/20 | 0.39 |
| ▸ | PGGT1B | P53609 | 11/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8156822 | 0.97 | FNTA (0.41) | FNTAFNTBPGGT1B | |
| SCHEMBL8150556 | 0.89 | FNTA (0.41) | FNTAFNTBPGGT1B | |
| SCHEMBL8157261 | 0.87 | FNTA (0.39) | FNTAFNTBPGGT1B | |
| SCHEMBL8143437 | 0.86 | FNTA (0.43) | FNTAFNTBPGGT1B | |
| SCHEMBL8149552 | 0.85 | FNTA (0.41) | FNTAFNTBPGGT1B | |
| SCHEMBL8154241 | 0.85 | FNTA (0.48) | FNTAFNTBPGGT1B | |
| SCHEMBL8155427 | 0.84 | FNTA (0.41) | FNTAFNTBPGGT1B | |
| SCHEMBL8143478 | 0.83 | FNTA (0.47) | FNTAFNTBPGGT1B | |
| SCHEMBL8154439 | 0.83 | FNTA (0.40) | FNTAFNTBPGGT1B | |
| SCHEMBL8155314 | 0.83 | FNTA (0.48) | FNTAFNTBPGGT1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0951285-A1 | INHIBITORS OF FARNESYL-PROTEIN TRANSFERASE | Merck & Co., Inc. (US) | 1999-10-27 | — | — | EP | claimed |
| WO-1998029119-A1 | INHIBITORS OF FARNESYL-PROTEIN TRANSFERASE | MERCK & CO., INC. (US) | 1998-07-09 | — | — | WO | claimed |
| US-6077853-A | Inhibitors of farnesyl-protein transferase | MERCK & CO., INC. (US) | 2000-06-20 | — | — | US | disclosed |
| EP-0951285-A1 | INHIBITORS OF FARNESYL-PROTEIN TRANSFERASE | Merck & Co., Inc. (US) | 1999-10-27 | — | — | EP | disclosed |
| WO-1998029119-A1 | INHIBITORS OF FARNESYL-PROTEIN TRANSFERASE | MERCK & CO., INC. (US) | 1998-07-09 | — | — | WO | disclosed |