Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F10 | P00742 | 20/20 | 0.75 |
| ▸ | PRSS1 | P07477 | 3/20 | 0.75 |
| ▸ | PRSS2 | P07478 | 3/20 | 0.75 |
| ▸ | PRSS3 | P35030 | 3/20 | 0.75 |
| ▸ | F2 | P00734 | 2/20 | 0.75 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6283571 | 0.76 | F10 (0.62) | F10PRSS1PRSS2PRSS3F2 | |
| SCHEMBL6286203 | 0.75 | F10 (0.80) | F10PRSS1PRSS2PRSS3F2 | |
| SCHEMBL8162653 | 0.74 | F10 (1.00) | F10PRSS1PRSS2PRSS3F2 | |
| SCHEMBL8163349 | 0.72 | F10 (0.90) | F10 | |
| SCHEMBL8170828 | 0.71 | F10 (0.74) | F10PRSS1PRSS2PRSS3F2 | |
| SCHEMBL12131737 | 0.71 | F10 (0.61) | F10PRSS1PRSS2PRSS3F2 | |
| SCHEMBL11528600 | 0.71 | CA1 (0.59) | F10 | |
| SCHEMBL8170658 | 0.70 | F10 (0.76) | F10PRSS1PRSS2PRSS3F2 | |
| SCHEMBL8163861 | 0.70 | F10 (1.00) | F10 | |
| SCHEMBL8162846 | 0.70 | F10 (0.88) | F10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040116399-A1 | Inhibitors of factor Xa | MILLENNIUM PHARMACEUTICALS, INC. | 2004-06-17 | — | — | US | disclosed |