SCHEMBL8157345

SCHEMBL8157345

C=CC/C=C(\C)CCCCCC/C=C(\C)CCC

nearest known ligand 0.38

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TSHR P16473 3/20 0.38
SQLE Q14534 3/20 0.37
ALDH1A1 P00352 3/20 0.33
LSS P48449 2/20 0.33
LMNA P02545 2/20 0.33
ABCC4 O15439 1/20 0.33
MAPT P10636 1/20 0.33
KMT2A Q03164 1/20 0.32
DUSP3 P51452 1/20 0.32
PTPN7 P35236 1/20 0.32
FAAH O00519 1/20 0.32
KDM4E B2RXH2 1/20 0.32
FFAR1 O14842 1/20 0.32
FABP3 P05413 1/20 0.32
CYP3A4 P08684 1/20 0.32
F7 P08709 1/20 0.32
CYP19A1 P11511 1/20 0.32
F3 P13726 1/20 0.32
FABP4 P15090 1/20 0.32
HPGD P15428 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8157346 1.00 TSHR (0.38) TSHRSQLEALDH1A1LSSLMNA
SCHEMBL846848 0.84
SCHEMBL846847 0.84
SCHEMBL3641069 0.84
SCHEMBL847474 0.83 TSHR (0.40) TSHRSQLEALDH1A1LSSKMT2A
SCHEMBL847473 0.83 TSHR (0.40) TSHRSQLEALDH1A1LSSKMT2A
SCHEMBL29284196 0.81 TSHR (0.56) TSHRSQLEALDH1A1LSSLMNA
SCHEMBL29284307 0.81 TSHR (0.56) TSHRSQLEALDH1A1LSSLMNA
SCHEMBL29284415 0.81 TSHR (0.61) TSHRALDH1A1LSSLMNAABCC4
SCHEMBL29284458 0.81 TSHR (0.56) TSHRSQLEALDH1A1LSSLMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0691354-B1 Unsaturated copolymer of ethylene and process for preparing the same MITSUI CHEMICALS INC (JP) 2000-04-12 EP disclosed
US-5837791-A WITH ANOTHER ALPHA-OLEFIN AND AT LEAST ONE NONCONJUGATED TRIENE OR TETRAENE MITSUI PETROCHEMICAL INDUSTRIES, LTD. (JP) 1998-11-17 US disclosed
EP-0691354-A1 Unsaturated copolymer of ethylene and process for preparing the same MITSUI PETROCHEMICAL INDUSTRIES, LTD. (JP) 1996-01-10 EP disclosed