Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8157697 | 1.00 | SRD5A1 (0.66) | SRD5A1SRD5A2 | |
| SCHEMBL8158493 | 0.94 | SRD5A1 (0.62) | SRD5A1SRD5A2 | |
| SCHEMBL8016930 | 0.86 | SRD5A1 (0.65) | SRD5A1SRD5A2 | |
| SCHEMBL8163935 | 0.85 | SRD5A1 (0.60) | SRD5A1SRD5A2 | |
| SCHEMBL8020976 | 0.85 | SRD5A1 (0.58) | SRD5A1SRD5A2 | |
| SCHEMBL8155921 | 0.83 | SRD5A1 (0.66) | SRD5A1SRD5A2 | |
| SCHEMBL8155923 | 0.83 | SRD5A1 (0.66) | SRD5A1SRD5A2 | |
| SCHEMBL8016786 | 0.80 | SRD5A1 (0.64) | SRD5A1SRD5A2 | |
| SCHEMBL8163312 | 0.79 | SRD5A1 (0.67) | SRD5A1SRD5A2 | |
| SCHEMBL8163315 | 0.79 | SRD5A1 (0.67) | SRD5A1SRD5A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6046183-A | SYNERGISTIC MIXTURE OF FINASTERIDE AND DOXAZOSIN | MERCK & CO., INC. (US) | 2000-04-04 | — | — | US | disclosed |
| US-5994362-A | ADMINISTERING FINASTERIDE AND CASODEX | MERCK & CO., INC. (US) | 1999-11-30 | — | — | US | disclosed |
| US-5753641-A | SYNERGISTIC THERAPY COMPRISING FINASTERIDE AND TERAZOSIN DRUGS | MERCK & CO., INC. (US) | 1998-05-19 | — | — | US | disclosed |
| US-5710275-A | ENZYME AND HORMONE INHIBITORS | MERCK & CO., INC. (US) | 1998-01-20 | — | — | US | disclosed |
| US-5693809-A | PREGNANES FOR TREATING ALOPECIA, ACNE AND SKIN DISORDER | MERCK & CO., INC. (US) | 1997-12-02 | — | — | US | disclosed |
| EP-0778284-A2 | New 7-beta-substituted-4-aza-5alpha-androstan-3-ones as 5alpha-reductase inhibitors | MERCK & CO. INC. (US) | 1997-06-11 | — | — | EP | disclosed |
| EP-0572166-A1 | New 7beta-substituted-4-aza-5a-androstan-3-ones as 5a-reductase inhibitors | MERCK & CO. INC. (US) | 1993-12-01 | — | — | EP | disclosed |
| US-5162332-A | Selected 17 β-polyaroyl-4-aza-5 α-androst-1-en-3-ones as steroidal reductase inhibitors | MERCK & CO., INC. (US) | 1992-11-10 | — | — | US | disclosed |
| EP-0462665-A2 | Selected 17beta-polyaroyl-4-aza-5alpha-androst-1-en-3-ones as steroidal reductase inhibitors | MERCK & CO. INC. (US) | 1991-12-27 | — | — | EP | disclosed |