SCHEMBL8157809

SCHEMBL8157809

CCCOC(C)CCc1ccc(O)cc1

nearest known ligand 0.55

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SLC6A2 P23975 5/20 0.46
SLC6A4 P31645 5/20 0.46
ESR1 P03372 4/20 0.46
SLC6A3 Q01959 4/20 0.46
LMNA P02545 4/20 0.46
HIF1A Q16665 4/20 0.46
ADRA2A P08913 3/20 0.46
ADORA3 P0DMS8 3/20 0.46
KDM4E B2RXH2 3/20 0.46
ADRB3 P13945 3/20 0.46
TACR2 P21452 2/20 0.46
CYP3A4 P08684 2/20 0.46
HSD17B10 Q99714 2/20 0.46
EGFR P00533 2/20 0.46
LCK P06239 2/20 0.46
ADRA2B P18089 2/20 0.46
ADRA2C P18825 2/20 0.46
PTGS2 P35354 2/20 0.46
ALDH1A1 P00352 1/20 0.46
SHBG P04278 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8156585 0.95 SLC6A2 (0.42) SLC6A2SLC6A4ESR1SLC6A3LMNA
SCHEMBL9396860 0.90 ESR1 (0.51) SLC6A2SLC6A4ESR1SLC6A3LMNA
SCHEMBL14685935 0.87 ESR1 (0.57) SLC6A2SLC6A4ESR1SLC6A3LMNA
SCHEMBL9253919 0.86 ESR1 (0.46) SLC6A2SLC6A4ESR1SLC6A3LMNA
SCHEMBL14685950 0.86 ESR1 (0.46) SLC6A2SLC6A4ESR1SLC6A3LMNA
SCHEMBL9259723 0.83 ESR1 (0.51) SLC6A2SLC6A4ESR1SLC6A3LMNA
SCHEMBL1839615 0.82 SLC6A2 (0.50) SLC6A2SLC6A4ESR1SLC6A3LMNA
SCHEMBL9260228 0.82 TDP1 (0.45) SLC6A2SLC6A4ESR1SLC6A3LMNA
SCHEMBL9260132 0.82 ESR1 (0.54) SLC6A2SLC6A4ESR1SLC6A3LMNA
SCHEMBL25299457 0.81 ESR1 (0.57) SLC6A2SLC6A4ESR1SLC6A3LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2556819-A1 EXTERNAL SKIN PREPARATION Kao Corporation (JP) 2013-02-13 EP disclosed
EP-0806417-B1 Novel optically active benzene derivatives, process for producing the same and liquid-crystalline composition containing said derivatives as liquid-crystalline compound and light switching elements SUMITOMO CHEMICAL CO (JP) 2000-03-08 EP disclosed
US-5693251-A LIQUID CRYSTAL DISPLAYS; HIGH SPEED RESPONSE SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1997-12-02 US disclosed
EP-0806417-A1 Novel optically active benzene derivatives, process for producing the same and liquid-crystalline composition containing said derivatives as liquid-crystalline compound and light switching elements SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1997-11-12 EP disclosed
US-5389293-A Light switches SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1995-02-14 US disclosed
US-5374376-A Optically active aromatic compounds, preparation process therefor, liquid crystal materials and a light switching element SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1994-12-20 US disclosed
EP-0357435-B1 Optically active aromatic compounds, preparation process therefor, liquid crystal materials and a light switching element SUMITOMO CHEMICAL CO (JP) 1993-12-08 EP disclosed
EP-0360622-A2 Novel optically active benzene derivatives, process for producing the same and liquid-crystalline composition containing said derivatives as liquid-crystalline compound and light switching elements SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1990-03-28 EP disclosed
EP-0357435-A2 Optically active aromatic compounds, preparation process therefor, liquid crystal materials and a light switching element SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1990-03-07 EP disclosed