SCHEMBL8158332

SCHEMBL8158332

O=C(NCc1cn(-c2ccc(-n3ccccc3=O)cc2SO)nn1)c1ccc(Cl)s1

nearest known ligand 0.52

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
F10 P00742 20/20 0.52
F2 P00734 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1752612 0.93 F10 (0.51) F10F2
SCHEMBL1752019 0.90 F10 (0.49) F10
SCHEMBL1097660 0.89 F10 (0.54) F10F2
SCHEMBL8152050 0.88 F10 (0.53) F10F2
SCHEMBL1097704 0.88 F10 (0.59) F10
SCHEMBL1752250 0.88 F10 (0.53) F10F2
SCHEMBL1752613 0.87 F10 (0.52) F10F2
SCHEMBL1752265 0.87 F10 (0.52) F10F2
SCHEMBL8166605 0.87 F10 (0.52) F10F2
SCHEMBL1752281 0.87 F10 (0.52) F10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2008086226-A2 FACTOR XA INHIBITORS MILLENNIUM PHARMACEUTICALS, INC. (US) 2008-07-17 WO disclosed