SCHEMBL8158570

SCHEMBL8158570

Cc1cc(C(=O)Nc2ccc(C(=N)N(C)C)cn2)n(-c2ccc3cc(Cl)ccc3c2)n1

nearest known ligand 0.71

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
F10 P00742 20/20 0.71

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8166448 0.88 F10 (0.74) F10
SCHEMBL8170283 0.87 F10 (0.82) F10
SCHEMBL8170332 0.85 F10 (0.72) F10
SCHEMBL8166307 0.84 F10 (0.73) F10
SCHEMBL8169809 0.83 F10 (1.00) F10
SCHEMBL8165744 0.81 F10 (0.50) F10
SCHEMBL8170216 0.79 F10 (0.77) F10
SCHEMBL8169405 0.78 F10 (0.74) F10
SCHEMBL8163938 0.76 F10 (0.70) F10
SCHEMBL8158809 0.76 F10 (0.69) F10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20040116399-A1 Inhibitors of factor Xa MILLENNIUM PHARMACEUTICALS, INC. 2004-06-17 US disclosed
US-20040116399-A1 Inhibitors of factor Xa MILLENNIUM PHARMACEUTICALS, INC. 2004-06-17 US disclosed