SCHEMBL8158952

SCHEMBL8158952

CCCCCC(CCCC)(c1ccccc1)c1ccccc1

nearest known ligand 0.59

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
ESR1 P03372 4/20 0.59
ESR2 Q92731 4/20 0.59
SIGMAR1 Q99720 3/20 0.41
KIF11 P52732 2/20 0.41
GAA P10253 1/20 0.40
MEN1 O00255 3/20 0.40
KMT2A Q03164 3/20 0.40
ATM Q13315 1/20 0.40
EBP Q15125 1/20 0.39
KCNN4 O15554 1/20 0.39
LTA4H P09960 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7781763 0.98 ESR1 (0.55) ESR1ESR2SIGMAR1KIF11GAA
SCHEMBL4740369 0.96 ESR1 (0.53) ESR1ESR2SIGMAR1GAAMEN1
SCHEMBL8978824 0.96 ESR1 (0.53) ESR1ESR2SIGMAR1GAAMEN1
SCHEMBL10448023 0.96 ESR1 (0.53) ESR1ESR2SIGMAR1GAAMEN1
SCHEMBL7543600 0.96 ESR1 (0.63) ESR1ESR2SIGMAR1KIF11MEN1
SCHEMBL17923963 0.94 ESR1 (0.52) ESR1ESR2SIGMAR1GAAMEN1
SCHEMBL4740387 0.91 ESR1 (0.59) ESR1ESR2KIF11MEN1KMT2A
Hydrochloric Acid SCHEMBL7850978 0.89 ESR1 (0.57) ESR1ESR2KIF11MEN1KMT2A
SCHEMBL15563056 0.87 ESR1 (0.53) ESR1ESR2SIGMAR1KIF11MEN1
SCHEMBL1000400 0.87 ESR1 (0.46) ESR1ESR2SIGMAR1GAAMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5866514-A HIGH BOILING; ODORLESS; ANTISEPTICS, HERBICIES, INSECTICIDES NIPPON PETROCHEMICALS COMPANY, LIMITED (JP) 1999-02-02 US claimed
EP-0753255-B1 Pesticidal compositions comprising diarylalkanes NIPPON PETROCHEMICALS CO LTD (JP) 2000-12-20 EP disclosed
US-5866514-A HIGH BOILING; ODORLESS; ANTISEPTICS, HERBICIES, INSECTICIDES NIPPON PETROCHEMICALS COMPANY, LIMITED (JP) 1999-02-02 US disclosed
EP-0753255-A2 Pesticidal compositions comprising diarylalkanes NIPPON PETROCHEMICALS CO., LTD. (JP) 1997-01-15 EP disclosed