⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1273177 | 0.72 | — | — | |
| SCHEMBL815908 | 0.72 | — | — | |
| SCHEMBL13872305 | 0.72 | — | — | |
| SCHEMBL421325 | 0.72 | — | — | |
| SCHEMBL14268554 | 0.62 | — | — | |
| Iodomethane SCHEMBL3415879 | 0.62 | — | — | |
| Fluoromethane SCHEMBL12205012 | 0.62 | — | — | |
| SCHEMBL49765 | 0.61 | — | — | |
| Methylamine SCHEMBL1332656 | 0.58 | — | — | |
| Methylamine SCHEMBL421137 | 0.58 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8324190-B2 | Treatment of proliferative disorders with amino-substituted (E)-2,6- dialkoxystyryl 4-substituted benzylsulfones | Temple University—Of the Commonwealth System of Higher Education (US) | 2012-12-04 | — | — | US | disclosed |
| US-7932242-B2 | Anticancer agents; radiation and chemical resistance | TEMPLE UNIVERSITY - OF THE COMMONWEALTH SYSTEM OF HIGHER EDUCATION (US) | 2011-04-26 | — | — | US | disclosed |
| US-20110054131-A1 | CYCLOOLEFIN-BASED POLYMER COMPOUND, PREPARATION METHOD THEREOF AND SELECTIVE HYDROGENATION PROCESS | KOLON INDUSTRIES, INC. (KR) | 2011-03-03 | — | — | US | disclosed |
| US-20110040055-A1 | ELECTROCHROMIC CONJUGATED POLYMERS | NATIONAL CENTRAL UNIVERSITY (TW) | 2011-02-17 | — | — | US | disclosed |
| US-7744889-B2 | Alpha, beta-unsaturated sulfoxides for treating proliferative disorders | TEMPLE UNIVERSITY - OF THE COMMONWEALTH SYSTEM OF HIGHER EDUCATION (US) | 2010-06-29 | — | — | US | disclosed |
| US-7683219-B1 | Hydroformylation process | INDUSTRIAL TECHNOLOGY RESEARCH INSTITUTE (TW) | 2010-03-23 | — | — | US | disclosed |
| US-20100069678-A1 | HYDROFORMYLATION PROCESS | INDUSTRIAL TECHNOLOGY RESEARCH INSTITUTE (TW) | 2010-03-18 | — | — | US | disclosed |
| US-7638656-B2 | Reacting cyclic olefin compound with carbon monoxide and hydrogen in solvent in presence of metal-organophosphorus ligand complex catalyst to obtain hydroformylation product liquid containing cycloalkyl aldehydes, extracting with cycloalkyl alcohol, allowing mixture to separate, recovering extractant | INDUSTRIAL TECHNOLOGY RESEARCH INSTITUTE (TW) | 2009-12-29 | — | — | US | disclosed |
| US-20090281066-A1 | Treatment of proliferative disorders with amino-substituted (E)-2,6- dialkoxystyryl 4-substituted benzylsulfones | TEMPLE UNIVERSITY - OF THE COMMONWEALTH SYSTEM OF HIGHER EDUCATION (US) | 2009-11-12 | — | — | US | disclosed |
| US-7598232-B2 | Amino-substituted (E)-2,6-dialkoxystyryl 4-substituted-benzylsulfones for treating proliferative disorders | TEMPLE UNIVERSITY - OF THE COMMONWEALTH SYSTEM OF HIGHER EDUCATION (US) | 2009-10-06 | — | — | US | disclosed |
| US-20090171125-A1 | Reacting cyclic olefin compound with carbon monoxide and hydrogen in solvent in presence of metal-organophosphorus ligand complex catalyst to obtain hydroformylation product liquid containing cycloalkyl aldehydes, extracting with cycloalkyl alcohol, allowing mixture to separate, recovering extractant | INDUSTRIAL TECHNOLOGY RESEARCH INSTITUTE (TW) | 2009-07-02 | — | — | US | disclosed |
| US-20080058290-A1 | Substituted Phenoxy-and Phenylthio-Derivatives for Treating Proliferative Disorders | TEMPLE UNIVERSITY - OF THE COMMONWEALTH SYSTEM OF HIGHER EDUCATION (US) | 2008-03-06 | — | — | US | disclosed |