Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP26A1 | O43174 | 8/20 | 0.78 |
| ▸ | CYP24A1 | Q07973 | 6/20 | 0.78 |
| ▸ | CYP19A1 | P11511 | 4/20 | 0.74 |
| ▸ | CYP27A1 | Q02318 | 3/20 | 0.64 |
| ▸ | ACHE | P22303 | 2/20 | 0.62 |
| ▸ | DRD2 | P14416 | 1/20 | 0.52 |
| ▸ | HTR2A | P28223 | 1/20 | 0.52 |
| ▸ | HTR2C | P28335 | 1/20 | 0.52 |
| ▸ | HTR2B | P41595 | 1/20 | 0.52 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7245357 | 0.89 | CYP24A1 (0.80) | CYP26A1CYP24A1CYP19A1CYP27A1ACHE | |
| SCHEMBL5582493 | 0.88 | CYP19A1 (0.73) | CYP26A1CYP24A1CYP19A1CYP27A1ACHE | |
| SCHEMBL30462610 | 0.88 | CYP19A1 (0.73) | CYP26A1CYP24A1CYP19A1CYP27A1ACHE | |
| SCHEMBL8203668 | 0.86 | CYP26A1 (0.79) | CYP26A1CYP24A1CYP19A1CYP27A1ACHE | |
| SCHEMBL6827615 | 0.85 | CYP19A1 (1.00) | CYP26A1CYP24A1CYP19A1CYP27A1 | |
| SCHEMBL8938852 | 0.84 | CYP24A1 (0.73) | CYP26A1CYP24A1CYP19A1CYP27A1ACHE | |
| SCHEMBL2877992 | 0.84 | CYP26A1 (0.76) | CYP26A1CYP24A1CYP19A1CYP27A1ACHE | |
| SCHEMBL630276 | 0.80 | CYP24A1 (0.70) | CYP26A1CYP24A1CYP19A1CYP27A1DRD2 | |
| SCHEMBL29679457 | 0.80 | CYP24A1 (0.66) | CYP26A1CYP24A1CYP19A1CYP27A1SIGMAR1 | |
| SCHEMBL7244157 | 0.80 | CYP24A1 (0.66) | CYP26A1CYP24A1CYP19A1CYP27A1SIGMAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1044181-A1 | BENZYL AND BENZYLIDENE TETRALINS AND DERIVATIVES | UNIVERSITY COLLEGE CARDIFF CONSULTANTS LTD. (GB) | 2000-10-18 | — | — | EP | disclosed |
| WO-1999035115-A1 | BENZYL AND BENZYLIDENE TETRALINS AND DERIVATIVES | UNIVERSITY COLLEGE CARDIFF CONSULTANTS LIMITED (GB) | 1999-07-15 | — | — | WO | disclosed |