SCHEMBL8160474

SCHEMBL8160474

CCOC(=O)C[C@H]1CC[C@H](C(C)(C)CC)CC1

nearest known ligand 0.38

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LIPA P38571 1/20 0.38
GAA P10253 2/20 0.36
MGAM O43451 1/20 0.36
SI P14410 1/20 0.36
MGAM2 Q2M2H8 1/20 0.36
JAK2 O60674 1/20 0.35
JAK1 P23458 1/20 0.35
TYK2 P29597 1/20 0.35
JAK3 P52333 1/20 0.35
ALDH1A1 P00352 3/20 0.34
TRPA1 O75762 1/20 0.34
TDP1 Q9NUW8 1/20 0.34
PARP14 Q460N5 1/20 0.33
S1PR5 Q9H228 1/20 0.33
POLB P06746 3/20 0.33
KMT2A Q03164 2/20 0.33
KDM4E B2RXH2 1/20 0.33
LMNA P02545 1/20 0.33
CYP1A2 P05177 1/20 0.33
CYP3A4 P08684 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25957888 0.88 LIPA (0.41) LIPAGAAMGAMSIMGAM2
SCHEMBL29228545 0.86 LIPA (0.51) LIPAGAAMGAMSIMGAM2
SCHEMBL2721040 0.84
SCHEMBL4269494 0.81 LIPA (0.42) LIPAGAAMGAMSIMGAM2
SCHEMBL584738 0.79 LIPA (0.42) LIPAGAAALDH1A1TDP1POLB
SCHEMBL14473403 0.79 MGAM (0.41) GAAMGAMSIMGAM2JAK2
SCHEMBL12590379 0.79 MGAM (0.41) GAAMGAMSIMGAM2JAK2
SCHEMBL14389978 0.78 MGAM (0.44) GAAMGAMSIMGAM2JAK2
SCHEMBL14389976 0.78 MGAM (0.44) GAAMGAMSIMGAM2JAK2
SCHEMBL7790319 0.77 MGAM (0.40) GAAMGAMSIMGAM2JAK2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1029845-A1 2-(4-Tert-pentylcyclohexyl)acetaldehyde and its use as fragrance compound QUEST INTERNATIONAL B.V. (NL) 2000-08-23 EP disclosed