Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.54 |
| ▸ | GAA | P10253 | 1/20 | 0.54 |
| ▸ | LMNA | P02545 | 3/20 | 0.43 |
| ▸ | CCR1 | P32246 | 2/20 | 0.43 |
| ▸ | CCR5 | P51681 | 2/20 | 0.43 |
| ▸ | CCR8 | P51685 | 2/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | METAP1 | P53582 | 1/20 | 0.43 |
| ▸ | BLM | P54132 | 1/20 | 0.43 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.43 |
| ▸ | DOHH | Q9BU89 | 1/20 | 0.43 |
| ▸ | P4HTM | Q9NXG6 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.40 |
| ▸ | NPC1 | O15118 | 3/20 | 0.40 |
| ▸ | RAB9A | P51151 | 3/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | ATM | Q13315 | 1/20 | 0.40 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9332718 | 0.86 | KDM4E (0.63) | KDM4EGAALMNACCR1CCR5 | |
| SCHEMBL492201 | 0.84 | KDM4E (0.61) | KDM4EGAALMNACCR1CCR5 | |
| SCHEMBL8153468 | 0.84 | — | — | |
| SCHEMBL617390 | 0.78 | KDM4E (0.73) | KDM4EGAALMNACCR1CCR5 | |
| SCHEMBL19803916 | 0.77 | KDM4E (0.47) | KDM4EGAALMNACCR1CCR5 | |
| SCHEMBL29096269 | 0.76 | KDM4E (0.70) | KDM4EGAALMNACCR1CCR5 | |
| SCHEMBL29096270 | 0.76 | KDM4E (0.70) | KDM4EGAALMNACCR1CCR5 | |
| SCHEMBL492334 | 0.75 | KDM4E (0.45) | KDM4EGAALMNACCR1CCR5 | |
| SCHEMBL1400875 | 0.74 | — | — | |
| SCHEMBL21609885 | 0.74 | KDM4E (0.54) | KDM4EGAALMNACCR1CCR5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 23 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0386834-B1 | CARBONYLATION CATALYST SYSTEM | SHELL INTERNATIONALE RESEARCHMAATSCHAPPIJ B.V. (NL) | 1993-02-03 | — | — | EP | claimed |
| EP-0386834-A1 | Carbonylation catalyst system | SHELL INTERNATIONALE RESEARCHMAATSCHAPPIJ B.V. (NL) | 1990-09-12 | — | — | EP | claimed |
| EP-0696474-B1 | Catalytic systems and methods for carbonylation | DAICEL CHEM (JP) | 2000-05-17 | — | — | EP | disclosed |
| EP-0948999-A1 | Catalytic systems and method for carbonylation | DAICEL CHEMICAL INDUSTRIES, LTD. (JP) | 1999-10-13 | — | — | EP | disclosed |
| US-5869738-A | OF AN OLEFIN WITH CARBON MONOXIDE PRODUCING AN ACID | DAICEL CHEMICAL INDUSTRIES, LTD. (JP) | 1999-02-09 | — | — | US | disclosed |
| US-5731255-A | GROUP VIII METAL SOURCE, LIGAND, ACID | DAICEL CHEMICAL INDUSTRIES, LTD. (JP) | 1998-03-24 | — | — | US | disclosed |
| EP-0696474-A2 | Catalytic systems and methods for carbonylation | DAICEL CHEMICAL INDUSTRIES, LTD. (JP) | 1996-02-14 | — | — | EP | disclosed |
| EP-0441447-B1 | Carbonylation catalyst process | SHELL INT RESEARCH (NL) | 1994-11-30 | — | — | EP | disclosed |
| EP-0441446-B1 | Carbonylation catalyst system | SHELL INT RESEARCH (NL) | 1994-05-04 | — | — | EP | disclosed |
| EP-0441445-B1 | Preparation of amides | SHELL INT RESEARCH (NL) | 1994-05-04 | — | — | EP | disclosed |
| EP-0386834-B1 | CARBONYLATION CATALYST SYSTEM | SHELL INTERNATIONALE RESEARCHMAATSCHAPPIJ B.V. (NL) | 1993-02-03 | — | — | EP | disclosed |
| US-5128475-A | PREPARATION OF AMIDES | SHELL OIL COMPANY (US) | 1992-07-07 | — | — | US | disclosed |
| US-5124300-A | Group 8 metal, aromatic phosphine, proton source, tertiary amine | SHELL OIL COMPANY (US) | 1992-06-23 | — | — | US | disclosed |
| EP-0489472-A2 | Carbonylation process and catalyst composition | SHELL INTERNATIONALE RESEARCHMAATSCHAPPIJ B.V. (NL) | 1992-06-10 | — | — | EP | disclosed |
| US-5103043-A | CARBONYLATION CATALYST SYSTEM | SHELL OIL COMPANY (US) | 1992-04-07 | — | — | US | disclosed |
| EP-0441446-A1 | Carbonylation catalyst system | SHELL INTERNATIONALE RESEARCHMAATSCHAPPIJ B.V. (NL) | 1991-08-14 | — | — | EP | disclosed |
| EP-0441447-A1 | Carbonylation catalyst process | SHELL INTERNATIONALE RESEARCHMAATSCHAPPIJ B.V. (NL) | 1991-08-14 | — | — | EP | disclosed |
| EP-0441445-A2 | Preparation of amides | SHELL INTERNATIONALE RESEARCHMAATSCHAPPIJ B.V. (NL) | 1991-08-14 | — | — | EP | disclosed |
| US-5028576-A | Carbonylation catalyst system | SHELL OIL COMPANY (US) | 1991-07-02 | — | — | US | disclosed |
| EP-0386834-A1 | Carbonylation catalyst system | SHELL INTERNATIONALE RESEARCHMAATSCHAPPIJ B.V. (NL) | 1990-09-12 | — | — | EP | disclosed |