Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TNFRSF1A | P19438 | 1/20 | 0.73 |
| ▸ | DPP4 | P27487 | 3/20 | 0.68 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.68 |
| ▸ | MAPT | P10636 | 6/20 | 0.67 |
| ▸ | CYP1A1 | P04798 | 3/20 | 0.67 |
| ▸ | CYP1B1 | Q16678 | 3/20 | 0.67 |
| ▸ | LMNA | P02545 | 3/20 | 0.67 |
| ▸ | HPGD | P15428 | 1/20 | 0.67 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.66 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.66 |
| ▸ | NPC1 | O15118 | 2/20 | 0.66 |
| ▸ | RAB9A | P51151 | 2/20 | 0.66 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.63 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.58 |
| ▸ | MAOB | P27338 | 1/20 | 0.58 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.57 |
| ▸ | ATM | Q13315 | 1/20 | 0.57 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.57 |
| ▸ | MEN1 | O00255 | 1/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8161195 | 1.00 | TNFRSF1A (0.73) | TNFRSF1ADPP4PTPN1MAPTCYP1A1 | |
| SCHEMBL9115191 | 0.99 | TNFRSF1A (0.71) | TNFRSF1ADPP4PTPN1MAPTCYP1A1 | |
| SCHEMBL7192316 | 0.98 | TNFRSF1A (0.76) | TNFRSF1ADPP4PTPN1MAPTCYP1A1 | |
| SCHEMBL7192320 | 0.98 | TNFRSF1A (0.76) | TNFRSF1ADPP4PTPN1MAPTCYP1A1 | |
| SCHEMBL9114708 | 0.93 | TNFRSF1A (0.76) | TNFRSF1ADPP4PTPN1MAPTCYP1A1 | |
| SCHEMBL9115776 | 0.93 | TNFRSF1A (0.76) | TNFRSF1ADPP4PTPN1MAPTCYP1A1 | |
| SCHEMBL9113143 | 0.88 | TNFRSF1A (0.68) | TNFRSF1ADPP4PTPN1MAPTCYP1A1 | |
| SCHEMBL9112510 | 0.88 | TNFRSF1A (0.80) | TNFRSF1ADPP4PTPN1MAPTCYP1A1 | |
| SCHEMBL9112505 | 0.88 | TNFRSF1A (0.80) | TNFRSF1ADPP4PTPN1MAPTCYP1A1 | |
| SCHEMBL29575068 | 0.87 | TNFRSF1A (0.74) | TNFRSF1ADPP4PTPN1MAPTCYP1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0996432-A2 | BIOLOGICALLY ACTIVE 1,3-BIS-AROMATIC-PROP-2-EN-1-ONES, 1,3-BIS-AROMATIC-PROPAN-1-ONES, AND 1,3-BIS-AROMATIC-PROP-2-YN-1-ONES | STATENS SERUMINSTITUT (DK) | 2000-05-03 | — | — | EP | disclosed |
| WO-1999000114-A2 | BIOLOGICALLY ACTIVE 1,3-BIS-AROMATIC-PROP-2-EN-1-ONES, 1,3-BIS-AROMATIC-PROPAN-1-ONES, AND 1,3-BIS-AROMATIC-PROP-2-YN-1-ONES | STATENS SERUM INSTITUT (DK) | 1999-01-07 | — | — | WO | disclosed |