Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP4 | P27487 | 2/20 | 0.45 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.45 |
| ▸ | DPP9 | Q86TI2 | 1/20 | 0.45 |
| ▸ | ELANE | P08246 | 9/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.39 |
| ▸ | CMA1 | P23946 | 2/20 | 0.39 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.38 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.38 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.38 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2756268 | 0.86 | CYP3A4 (0.49) | DPP4DPP8DPP9ELANECYP3A4 | |
| SCHEMBL3268700 | 0.86 | CYP3A4 (0.49) | DPP4DPP8DPP9ELANECYP3A4 | |
| SCHEMBL13071010 | 0.84 | CYP3A4 (0.47) | DPP4DPP8DPP9ELANECYP3A4 | |
| SCHEMBL8143604 | 0.82 | CMA1 (0.53) | ELANECMA1 | |
| SCHEMBL8161391 | 0.82 | ELANE (0.43) | DPP4DPP8DPP9ELANECYP3A4 | |
| SCHEMBL8161374 | 0.82 | CMA1 (0.53) | ELANECMA1 | |
| SCHEMBL3778456 | 0.81 | DPP4 (0.49) | DPP4DPP8DPP9ELANE | |
| SCHEMBL8167988 | 0.79 | DPP4 (0.45) | DPP4DPP8DPP9ELANECMA1 | |
| SCHEMBL8167984 | 0.78 | SMN1; SMN2 (0.55) | DPP4DPP8DPP9ELANE | |
| SCHEMBL12566960 | 0.77 | DPP4 (0.51) | DPP4DPP8DPP9ELANECYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008095058-A1 | HCV PROTEASE INHIBITORS | TAIGEN BIOTECHNOLOGY CO. LTD. (TW) | 2008-08-07 | — | — | WO | disclosed |