Ethyl Propionate

Ethyl Propionate

SCHEMBL8162256

CCO.CCOC(=O)CC

nearest known ligand 0.60

Full drug profile on Sugi Atlas →

Known targets — ChEMBL curated mechanism

MMP1MMP13MMP7MMP8polrplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO

The experimentally established mechanism targets of Ethyl Propionate. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GAA P10253 2/20 0.60
MGAM O43451 1/20 0.60
SI P14410 1/20 0.60
MGAM2 Q2M2H8 1/20 0.60
ALDH1A1 P00352 5/20 0.55
TRPA1 O75762 1/20 0.55
SOAT1 P35610 1/20 0.52
LMNA P02545 1/20 0.48
HSD17B10 Q99714 1/20 0.48
CYP1A2 P05177 2/20 0.46
NAAA Q02083 1/20 0.46
ALOX15 P16050 1/20 0.46
CYP4F2 P78329 2/20 0.42
CYP4A11 Q02928 2/20 0.42
HPGD P15428 1/20 0.41
CYP2C19 P33261 1/20 0.41
BLM P54132 1/20 0.41
WRN Q14191 1/20 0.41
HIF1A Q16665 1/20 0.41
CA12 O43570 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Ethyl Propionate SCHEMBL1332690 0.94
Ethyl Propionate SCHEMBL4883389 0.94
Ethyl Propionate SCHEMBL16045 0.94
Ethyl Propionate SCHEMBL1868177 0.94 GAA (0.67) GAAMGAMSIMGAM2ALDH1A1
Ethyl Propionate SCHEMBL28745725 0.92 GAA (0.52) GAAMGAMSIMGAM2ALDH1A1
Ethyl Propionate SCHEMBL875633 0.92 GAA (0.57) GAAMGAMSIMGAM2ALDH1A1
Ethyl Propionate SCHEMBL25183273 0.91
Ethyl Propionate SCHEMBL4449050 0.91
Ethyl Propionate SCHEMBL7036034 0.91
Ethyl Propionate SCHEMBL25298294 0.91

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-116354792-B Method for preparing cyclopentanol from cyclopentene 福州大学 2024-06-04 CN disclosed
CN-116354792-A Method for preparing cyclopentanol from cyclopentene and working method thereof 福州大学 2023-06-30 CN disclosed
CN-105496984-B A kind of Cefixime Capsules and preparation method thereof that quality is stable 石药集团欧意药业有限公司 2019-01-11 CN disclosed
CN-105496984-A Cefixime capsule stable in quality and preparation method thereof CSPC PHARMACEUTICAL GROUP OUYI PHARMA CO LTD 2016-04-20 CN disclosed
CN-101611033-B Indole derivatives as S1P1 receptor agonists GLAXO GROUP LTD 2012-10-31 CN disclosed
CN-101663297-A Oxadiazole substituted indazole derivatives for use as sphingosine 1-phosphate (s1p) agonists GLAXO GROUP LTD 2010-03-03 CN disclosed
CN-101611033-A Indole derivatives as S1P1 receptor agonists GLAXO GROUP LTD (GB) 2009-12-23 CN disclosed
CN-100374438-C Pre-organized tricyclic integrase inhibitor compounds GILEAD SCIENCES INC (US) 2008-03-12 CN disclosed
CN-1726212-A Pre-organized tricyclic integrase inhibitor compounds GILEAD SCIENCES INC (US) 2006-01-25 CN disclosed
EP-1051385-A1 PROCESSES FOR PREPARING OXYGENATES AND CATALYSTS THEREFOR UNION CARBIDE CHEMICALS & PLASTICS TECHNOLOGY CORPORATION (US) 2000-11-15 EP disclosed
WO-1999038836-A1 PROCESSES FOR PREPARING OXYGENATES AND CATALYSTS THEREFOR UNION CARBIDE CHEMICALS & PLASTICS TECHNOLOGY CORPORATION (US) 1999-08-05 WO disclosed