Known targets — ChEMBL curated mechanism
ADRA2AADRA2BADRA2CADRB2AGTR1AVPR1AAVPR1BAVPR2BDKRB2CALCRCHRNA3CHRNB4ESR1ESR2GHSRGNRHRGSC1HSPA8MALT1MC1RMC4RNOS1NOS2NOS3OPRK1OXTRRAMP1RAMP2RAMP3SCN5ASSTR1SSTR2SSTR3SSTR4SSTR5dacAdacBdacCfolPftsImrcAmrcBmrdArplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Acetic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR3 | O14843 | 1/20 | 0.54 |
| ▸ | LCK | P06239 | 1/20 | 0.54 |
| ▸ | FYN | P06241 | 1/20 | 0.54 |
| ▸ | CA1 | P00915 | 2/20 | 0.47 |
| ▸ | CA4 | P22748 | 3/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | TSHR | P16473 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | THPO | P40225 | 1/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.31 |
| ▸ | BLM | P54132 | 1/20 | 0.31 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.31 |
| ▸ | FAHD1 | Q6P587 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Acetic Acid SCHEMBL8349268 | 1.00 | FFAR3 (0.54) | FFAR3LCKFYNCA1CA4 | |
| Acetic Acid SCHEMBL28218335 | 1.00 | FFAR3 (0.54) | FFAR3LCKFYNCA1CA4 | |
| Acetic Acid SCHEMBL8169112 | 0.96 | FFAR3 (0.50) | FFAR3LCKFYNCA1CA4 | |
| Acetic Acid SCHEMBL9488865 | 0.96 | FFAR3 (0.50) | FFAR3LCKFYNCA1CA4 | |
| Acetic Acid SCHEMBL9138922 | 0.89 | FFAR3 (0.50) | FFAR3LCKFYNCA1CA4 | |
| Acetic Acid SCHEMBL9138928 | 0.89 | FFAR3 (0.50) | FFAR3LCKFYNCA1CA4 | |
| Acetic Acid SCHEMBL8164708 | 0.89 | FFAR3 (0.50) | FFAR3LCKFYNCA1CA4 | |
| Acetic Acid SCHEMBL8349273 | 0.89 | — | — | |
| Acetone SCHEMBL6314337 | 0.88 | CA1 (0.50) | FFAR3LCKFYNCA1CA4 | |
| Acetic Acid SCHEMBL28222310 | 0.87 | FFAR3 (0.41) | FFAR3LCKFYNCA1CA4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6153370-A | SELECTIVELY ADSORPTION OF SILVER HALIDE GRAINS AND SENSITIZING DYE | FUJI PHOTO FILM CO., LTD. (JP) | 2000-11-28 | — | — | US | disclosed |
| US-6143483-A | EMULSION EXCELLENT IN SENSITIVITY AND IN EACH OF SUPPRESSION OF DEPENDENCE ON A PROCESSING SOLUTION PH AND PRESERVABILITY OF LATENT IMAGE | FUJI PHOTO FILM CO. (JP) | 2000-11-07 | — | — | US | disclosed |
| US-6074810-A | COUPLERS FOR LAYERS OF SILVER HALIDE EMULSIONS | FUJI PHOTO FILM CO., LTD. (JP) | 2000-06-13 | — | — | US | disclosed |
| US-6048673-A | SILVER HALIDE MULTILAYER ELEMENT WITH RADIATION TRANSPARENT SUPPORT | FUJI PHOTO FILM CO., LTD. (JP) | 2000-04-11 | — | — | US | disclosed |