Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F10 | P00742 | 17/20 | 0.80 |
| ▸ | F2 | P00734 | 8/20 | 0.68 |
| ▸ | PRSS1 | P07477 | 5/20 | 0.68 |
| ▸ | PRSS2 | P07478 | 4/20 | 0.68 |
| ▸ | PRSS3 | P35030 | 4/20 | 0.68 |
| ▸ | KLKB1 | P03952 | 1/20 | 0.60 |
| ▸ | PROC | P04070 | 1/20 | 0.60 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8170306 | 0.89 | F10 (1.00) | F10F2PRSS1PRSS2PRSS3 | |
| SCHEMBL8168654 | 0.88 | F10 (1.00) | F10F2PRSS1PRSS2PRSS3 | |
| SCHEMBL8165499 | 0.87 | F10 (0.81) | F10F2PRSS1PRSS2PRSS3 | |
| SCHEMBL8158181 | 0.85 | F10 (0.78) | F10F2PRSS1PRSS2PRSS3 | |
| SCHEMBL8169475 | 0.84 | F10 (0.81) | F10F2PRSS1PRSS2PRSS3 | |
| SCHEMBL3829855 | 0.83 | F2 (0.89) | F10F2PRSS1PRSS2PRSS3 | |
| SCHEMBL8170777 | 0.81 | F10 (0.92) | F10F2PRSS1PRSS2PRSS3 | |
| SCHEMBL3831794 | 0.81 | F2 (1.00) | F10F2PRSS1PRSS2PRSS3 | |
| SCHEMBL8166019 | 0.80 | F10 (0.69) | F10F2PRSS1PRSS2PRSS3 | |
| SCHEMBL8158194 | 0.80 | F10 (0.84) | F10F2PRSS1PRSS2PRSS3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040116399-A1 | Inhibitors of factor Xa | MILLENNIUM PHARMACEUTICALS, INC. | 2004-06-17 | — | — | US | disclosed |