SCHEMBL8165136 — predicted protein targets

Predicted protein targets (top 10)

	gene	UniProt	supporting neighbours	confidence
▸	F10	P00742	19/20	0.85

▸	F2	P00734	7/20	0.72

▸	PRSS1	P07477	5/20	0.72

▸	PRSS2	P07478	5/20	0.72

▸	PRSS3	P35030	5/20	0.72

▸	KLK1	P06870	2/20	0.61

▸	F9	P00740	2/20	0.58

▸	PROC	P04070	2/20	0.58

▸	KLKB1	P03952	1/20	0.57

▸	CFH	P08603	1/20	0.57

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compound	similarity	top predicted	shared targets
SCHEMBL8169765	0.93	F10 (0.85)	F10F2PRSS1PRSS2PRSS3
SCHEMBL8165148	0.92	F10 (1.00)	F10F2PRSS1PRSS2PRSS3
SCHEMBL8163826	0.89	F10 (0.81)	F10F2PRSS1PRSS2PRSS3
SCHEMBL8165396	0.86	F10 (1.00)	F10F2PRSS1PRSS2PRSS3
SCHEMBL8169824	0.86	F10 (1.00)	F10F2PRSS1PRSS2PRSS3
SCHEMBL8168825	0.85	F10 (1.00)	F10F2PRSS1PRSS2PRSS3
SCHEMBL8164807	0.85	F10 (0.83)	F10F2PRSS1PRSS2PRSS3
SCHEMBL8159074	0.83	F10 (0.69)	F10F2PRSS1PRSS2PRSS3
SCHEMBL8163056	0.82	F10 (1.00)	F10F2PRSS1PRSS2PRSS3
SCHEMBL8163822	0.81	F10 (0.87)	F10F2PRSS1PRSS2PRSS3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

Patent	Title	Assignee	Published	Priority	Filing	Country	Status
US-20040116399-A1	Inhibitors of factor Xa	MILLENNIUM PHARMACEUTICALS, INC.	2004-06-17	—	—	US	disclosed