Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 1/20 | 0.34 |
| ▸ | CA2 | P00918 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 3/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.31 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.31 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 2/20 | 0.30 |
| ▸ | LMNA | P02545 | 2/20 | 0.30 |
| ▸ | HTT | P42858 | 2/20 | 0.30 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.30 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5952217 | 0.82 | CA1 (0.48) | CA1CA2ALDH1A1HSD17B10CYP1A2 | |
| SCHEMBL6189449 | 0.78 | TP53 (0.34) | KMT2ARAB9AMEN1 | |
| SCHEMBL5952226 | 0.73 | CA1 (0.54) | CA1CA2ALDH1A1HSD17B10CYP1A2 | |
| SCHEMBL5951496 | 0.73 | TP53 (0.39) | KMT2AALDH1A1HSD17B10MAPTKDM4E | |
| SCHEMBL14983479 | 0.69 | CA1 (0.47) | CA1CA2ALDH1A1HSD17B10CYP1A2 | |
| SCHEMBL2400555 | 0.61 | ORAI1 (0.40) | KMT2AALDH1A1CYP1A2MAPTKDM4E | |
| SCHEMBL21076143 | 0.61 | CA1 (0.61) | CA1CA2KMT2ACYP1A2CYP2A6 | |
| SCHEMBL14983446 | 0.60 | CA1 (0.48) | CA1CA2ALDH1A1HSD17B10CYP1A2 | |
| SCHEMBL14983444 | 0.59 | CA1 (0.52) | CA1CA2KMT2AALDH1A1HSD17B10 | |
| SCHEMBL14983496 | 0.59 | TSHR (0.33) | KMT2AALDH1A1HSD17B10HPGDSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0968158-A1 | METHOD OF PREPARING SUBSTITUTED INDANONES, THE SUBSTITUTED INDANONES AND METALLOCENES PREPARED THEREFROM | Basell Polyolefine GmbH (DE) | 2000-01-05 | — | — | EP | disclosed |
| WO-1998040331-A1 | PREPARATION OF PREPARING SUBSTITUTED INDANONES | TARGOR GMBH (DE) | 1998-09-17 | — | — | WO | disclosed |