Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F10 | P00742 | 18/20 | 0.60 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.58 |
| ▸ | F2 | P00734 | 1/20 | 0.44 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.44 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.44 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8167211 | 0.98 | F10 (0.62) | F10KCNH2 | |
| SCHEMBL8165979 | 0.97 | F10 (0.63) | F10KCNH2 | |
| SCHEMBL8166644 | 0.93 | KCNH2 (0.57) | F10KCNH2 | |
| SCHEMBL8171351 | 0.92 | KCNH2 (0.59) | F10KCNH2 | |
| SCHEMBL8159704 | 0.91 | KCNH2 (0.58) | F10KCNH2 | |
| SCHEMBL8166537 | 0.89 | F10 (0.77) | F10 | |
| SCHEMBL8406118 | 0.88 | KCNH2 (0.60) | F10KCNH2 | |
| SCHEMBL8159663 | 0.87 | F10 (0.80) | F10 | |
| SCHEMBL8171224 | 0.86 | F10 (0.80) | F10 | |
| SCHEMBL8408304 | 0.86 | KCNH2 (0.62) | F10KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040116399-A1 | Inhibitors of factor Xa | MILLENNIUM PHARMACEUTICALS, INC. | 2004-06-17 | — | — | US | disclosed |