Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GNRHR | P30968 | 20/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8165422 | 0.82 | GNRHR (0.49) | GNRHRMEN1KMT2A | |
| SCHEMBL8160020 | 0.82 | GNRHR (0.43) | GNRHRMEN1KMT2A | |
| SCHEMBL7521084 | 0.81 | GNRHR (0.61) | GNRHRMEN1KMT2A | |
| SCHEMBL7518445 | 0.80 | GNRHR (0.53) | GNRHRMEN1KMT2A | |
| SCHEMBL8165658 | 0.80 | GNRHR (0.42) | GNRHRMEN1KMT2A | |
| SCHEMBL8160095 | 0.79 | GNRHR (0.53) | GNRHRMEN1KMT2A | |
| SCHEMBL8158803 | 0.77 | GNRHR (0.46) | GNRHRMEN1KMT2A | |
| SCHEMBL7498273 | 0.76 | GNRHR (0.67) | GNRHR | |
| SCHEMBL8166233 | 0.75 | GNRHR (0.79) | GNRHRMEN1KMT2A | |
| SCHEMBL8165696 | 0.71 | GNRHR (0.46) | GNRHRMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6015789-A | LUTEINIZING HORMONE RELEASING HORMONE AGONIST AND A LUTEINIZING HORMONE RELEASING HORMONE ANTAGONIST IN COMBINATION, | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 2000-01-18 | — | — | US | disclosed |
| US-5977132-A | GALACTORRHEA, HYPERPROLACTINEMIC OVULATION, PROLACTINOMA AND BRAIN TUMORS | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1999-11-02 | — | — | US | disclosed |
| US-5744479-A | PITUITARY HORMONE INHIBITOR | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1998-04-28 | — | — | US | disclosed |
| EP-0781774-A2 | Prolactin production inhibitory agents | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1997-07-02 | — | — | EP | disclosed |