Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F10 | P00742 | 18/20 | 0.77 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.49 |
| ▸ | F2 | P00734 | 1/20 | 0.44 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.44 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.44 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8158250 | 0.99 | F10 (0.76) | F10KCNH2F2PRSS1PRSS2 | |
| SCHEMBL8164880 | 0.88 | F10 (0.76) | F10KCNH2 | |
| SCHEMBL8158231 | 0.88 | F10 (0.81) | F10KCNH2 | |
| SCHEMBL8170222 | 0.87 | F10 (0.75) | F10KCNH2 | |
| SCHEMBL8166112 | 0.87 | F10 (0.81) | F10KCNH2 | |
| SCHEMBL8166139 | 0.87 | F10 (1.00) | F10 | |
| SCHEMBL8165515 | 0.86 | F10 (1.00) | F10 | |
| SCHEMBL8169288 | 0.84 | F10 (0.75) | F10 | |
| SCHEMBL8165680 | 0.82 | F10 (0.75) | F10KCNH2F2PRSS1PRSS2 | |
| SCHEMBL8169570 | 0.81 | F10 (0.75) | F10KCNH2F2PRSS1PRSS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040116399-A1 | Inhibitors of factor Xa | MILLENNIUM PHARMACEUTICALS, INC. | 2004-06-17 | — | — | US | disclosed |
| US-20040116399-A1 | Inhibitors of factor Xa | MILLENNIUM PHARMACEUTICALS, INC. | 2004-06-17 | — | — | US | disclosed |