Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F10 | P00742 | 19/20 | 0.61 |
| ▸ | F2 | P00734 | 11/20 | 0.61 |
| ▸ | PRSS1 | P07477 | 5/20 | 0.57 |
| ▸ | PRSS2 | P07478 | 4/20 | 0.56 |
| ▸ | PRSS3 | P35030 | 4/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8166242 | 0.91 | F10 (0.71) | F10F2PRSS1PRSS2PRSS3 | |
| SCHEMBL8166779 | 0.90 | F10 (0.61) | F10F2PRSS1PRSS2PRSS3 | |
| SCHEMBL8166928 | 0.90 | F10 (0.70) | F10F2PRSS1PRSS2PRSS3 | |
| SCHEMBL8166259 | 0.88 | F10 (0.68) | F10F2PRSS1PRSS2PRSS3 | |
| SCHEMBL8170658 | 0.84 | F10 (0.76) | F10F2PRSS1PRSS2PRSS3 | |
| SCHEMBL8165361 | 0.81 | F10 (0.58) | F10F2PRSS1PRSS2PRSS3 | |
| SCHEMBL8159253 | 0.81 | F10 (0.77) | F10F2PRSS1PRSS2PRSS3 | |
| SCHEMBL8166097 | 0.81 | F10 (0.71) | F10F2PRSS1PRSS2PRSS3 | |
| SCHEMBL8166664 | 0.80 | F10 (0.71) | F10F2PRSS1PRSS2PRSS3 | |
| SCHEMBL8159074 | 0.79 | F10 (0.69) | F10F2PRSS1PRSS2PRSS3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040116399-A1 | Inhibitors of factor Xa | MILLENNIUM PHARMACEUTICALS, INC. | 2004-06-17 | — | — | US | disclosed |