SCHEMBL8166319

SCHEMBL8166319

C=CC(=O)OC(CC)OS(=O)(=O)O

nearest known ligand 0.36

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
TSHR P16473 8/20 0.36
HPGD P15428 1/20 0.35
ALDH1A1 P00352 4/20 0.31
TP53 P04637 2/20 0.31
HIF1A Q16665 2/20 0.31
CYP3A4 P08684 1/20 0.31
HSD17B10 Q99714 1/20 0.31
THRB P10828 2/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8169316 0.86 TSHR (0.37) TSHRHPGDALDH1A1TP53HIF1A
SCHEMBL21905435 0.86 TSHR (0.36) TSHRHPGDALDH1A1TP53HIF1A
SCHEMBL1138627 0.82 TSHR (0.45) TSHRHPGDALDH1A1TP53HIF1A
SCHEMBL9155818 0.81 TSHR (0.41) TSHRHPGDALDH1A1TP53HIF1A
SCHEMBL2921941 0.79 TSHR (0.42) TSHRHPGDALDH1A1TP53HIF1A
SCHEMBL11315350 0.77 TSHR (0.41) TSHRHPGDALDH1A1TP53HIF1A
SCHEMBL28816507 0.77 TSHR (0.41) TSHRHPGDALDH1A1TP53HIF1A
SCHEMBL1068222 0.77 TSHR (0.41) TSHRHPGDALDH1A1TP53HIF1A
SCHEMBL5393796 0.77 TSHR (0.43) TSHRHPGDALDH1A1TP53HIF1A
SCHEMBL8165563 0.76 TSHR (0.37) TSHRALDH1A1THRB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0572984-B1 Fast-acting viscosity enhancers for gelatin solutions EASTMAN KODAK CO (US) 2000-10-04 EP disclosed
US-5994485-A BINDER COMPRISES A VINYL CHLORIDE/VINYL ACETATE COPOLYMER CHARACTERIZED IN THAT IT HAS A PEAK AT A SIGNAL POSITION OF FROM 6.0 TO 8.0 PPM IN THE 1 H-NMR MEASUREMENT. DENKI KAGAKU KOGYO KABUSHIKI KAISHA (JP) 1999-11-30 US disclosed
EP-0881240-A1 Vinyl chloride/vinyl acetate copolymer, binder for a magnetic recording medium, and magnetic recording medium DENKI KAGAKU KOGYO KABUSHIKI KAISHA (JP) 1998-12-02 EP disclosed
EP-0572984-A2 Fast-acting viscosity enhancers for gelatin solutions EASTMAN KODAK COMPANY (US) 1993-12-08 EP disclosed