SCHEMBL8167273 — predicted protein targets

Predicted protein targets (top 8)

	gene	UniProt	supporting neighbours	confidence
▸	CYP1A2	P05177	1/20	0.44

▸	CYP2A6	P11509	1/20	0.44

▸	UHRF1	Q96T88	1/20	0.36

▸	CSNK2A1	P68400	1/20	0.35

▸	AHR	P35869	2/20	0.33

▸	SLC6A2	P23975	1/20	0.32

▸	SLC6A4	P31645	1/20	0.32

▸	S1PR4	O95977	1/20	0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compound	similarity	top predicted	shared targets
SCHEMBL8171066	1.00	CYP1A2 (0.44)	CYP1A2CYP2A6UHRF1CSNK2A1AHR
SCHEMBL6844960	0.86	CYP1A2 (0.52)	CYP1A2CYP2A6UHRF1SLC6A2SLC6A4
SCHEMBL8166969	0.86	CYP1A2 (0.52)	CYP1A2CYP2A6UHRF1
SCHEMBL2996864	0.77	—	—
SCHEMBL6841915	0.77	—	—
SCHEMBL8160371	0.77	CYP1A2 (0.44)	CYP1A2CYP2A6UHRF1
SCHEMBL8166973	0.77	CYP1A2 (0.44)	CYP1A2CYP2A6UHRF1
SCHEMBL8160370	0.77	CYP1A2 (0.44)	CYP1A2CYP2A6UHRF1
SCHEMBL19532041	0.77	PDPK1 (0.44)	CSNK2A1AHR
SCHEMBL29567534	0.77	PDPK1 (0.44)	CSNK2A1AHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

Patent	Title	Assignee	Published	Priority	Filing	Country	Status
US-20040116399-A1	Inhibitors of factor Xa	MILLENNIUM PHARMACEUTICALS, INC.	2004-06-17	—	—	US	disclosed
US-20040116399-A1	Inhibitors of factor Xa	MILLENNIUM PHARMACEUTICALS, INC.	2004-06-17	—	—	US	disclosed