Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.88 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.75 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.75 |
| ▸ | HPGD | P15428 | 1/20 | 0.64 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.64 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Rh-5849 SCHEMBL1538531 | 0.94 | POLB (1.00) | POLBCYP3A4CYP2C9HPGDSMN1; SMN2 | |
| SCHEMBL9496264 | 0.89 | POLB (0.85) | POLBCYP3A4CYP2C9HPGDSMN1; SMN2 | |
| SCHEMBL8773665 | 0.89 | POLB (0.85) | POLBCYP3A4CYP2C9HPGDSMN1; SMN2 | |
| SCHEMBL9825459 | 0.89 | POLB (0.85) | POLBCYP3A4CYP2C9HPGDSMN1; SMN2 | |
| SCHEMBL9826327 | 0.89 | POLB (0.85) | POLBCYP3A4CYP2C9HPGDSMN1; SMN2 | |
| SCHEMBL9877264 | 0.89 | POLB (0.85) | POLBCYP3A4CYP2C9HPGDSMN1; SMN2 | |
| SCHEMBL9825457 | 0.89 | POLB (0.85) | POLBCYP3A4CYP2C9HPGDSMN1; SMN2 | |
| SCHEMBL9714077 | 0.89 | POLB (0.85) | POLBCYP3A4CYP2C9HPGDSMN1; SMN2 | |
| SCHEMBL9714073 | 0.89 | POLB (0.85) | POLBCYP3A4CYP2C9HPGDSMN1; SMN2 | |
| SCHEMBL9826325 | 0.89 | POLB (0.85) | POLBCYP3A4CYP2C9HPGDSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6013836-A | PARTICULARLY ACTIVE AGAINST MOTHS AND BEETLES AND THEIR INSECT GROWTH REGULATING ACTIVITY WITHOUT ADVERSE IMPACT ON BENEFICIAL INSECTS; CROPS; FORESTRY | ROHM AND HAAS COMPANY (US) | 2000-01-11 | — | — | US | disclosed |
| EP-0236618-A2 | Insecticidal N'-substituted-N,N'-diacylhydrazines | ROHM AND HAAS COMPANY (US) | 1987-09-16 | — | — | EP | disclosed |