Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 6/20 | 0.63 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.63 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.63 |
| ▸ | TSHR | P16473 | 1/20 | 0.63 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 3/20 | 0.39 |
| ▸ | NPC1 | O15118 | 2/20 | 0.39 |
| ▸ | FKBP1A | P62942 | 2/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | USP2 | O75604 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | THRB | P10828 | 3/20 | 0.38 |
| ▸ | THRA | P10827 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8168732 | 0.99 | SMN1; SMN2 (0.62) | SMN1; SMN2MAPK1ALDH1A1TSHRHRH3 | |
| SCHEMBL2690853 | 0.99 | SMN1; SMN2 (0.62) | SMN1; SMN2MAPK1ALDH1A1TSHRHRH3 | |
| SCHEMBL5822546 | 0.96 | SMN1; SMN2 (0.64) | SMN1; SMN2MAPK1ALDH1A1TSHRHRH3 | |
| SCHEMBL278825 | 0.94 | SMN1; SMN2 (0.71) | SMN1; SMN2MAPK1ALDH1A1TSHRHRH3 | |
| SCHEMBL8182160 | 0.93 | SMN1; SMN2 (0.60) | SMN1; SMN2MAPK1ALDH1A1TSHRHRH3 | |
| SCHEMBL8175957 | 0.91 | SMN1; SMN2 (0.67) | SMN1; SMN2MAPK1ALDH1A1TSHRHRH3 | |
| SCHEMBL10649119 | 0.89 | SMN1; SMN2 (0.64) | SMN1; SMN2MAPK1ALDH1A1TSHRHRH3 | |
| SCHEMBL10883782 | 0.89 | SMN1; SMN2 (0.74) | SMN1; SMN2MAPK1ALDH1A1TSHRHRH3 | |
| SCHEMBL10885407 | 0.88 | SMN1; SMN2 (0.63) | SMN1; SMN2MAPK1ALDH1A1TSHRHRH3 | |
| SCHEMBL9679909 | 0.88 | SMN1; SMN2 (0.63) | SMN1; SMN2MAPK1ALDH1A1TSHRHRH3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6022906-A | α-aminoacetophenone photoinitiators | CIBA SPECIALTY CHEMICALS CORPORATION (US) | 2000-02-08 | — | — | US | disclosed |