SCHEMBL8168218

SCHEMBL8168218

CCOc1n[c]nc(Cl)n1

nearest known ligand 0.35

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
POLB P06746 1/20 0.35
MEN1 O00255 1/20 0.33
CYP1A2 P05177 1/20 0.33
KMT2A Q03164 1/20 0.33
KDM4E B2RXH2 1/20 0.32
NFKB1 P19838 1/20 0.32
MAT2A P31153 1/20 0.30
MAPK1 P28482 1/20 0.30
SMN1; SMN2 Q16637 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5936054 0.84 MEN1 (0.39) POLBMEN1CYP1A2KMT2AMAT2A
SCHEMBL5691816 0.80 NR5A1 (0.33) SMN1; SMN2
SCHEMBL11152741 0.79 TSHR (0.31)
SCHEMBL9481789 0.77 PDE4B (0.39) POLBMEN1CYP1A2KMT2AMAT2A
SCHEMBL6293233 0.77 MEN1 (0.34) MEN1CYP1A2KMT2AMAT2AMAPK1
SCHEMBL4651689 0.76
SCHEMBL6051593 0.75 POLB (0.48) POLBMEN1CYP1A2KMT2AKDM4E
SCHEMBL1391361 0.75 KDM4E (0.44) POLBMEN1CYP1A2KMT2AKDM4E
SCHEMBL8027740 0.72 MEN1 (0.43) POLBMEN1CYP1A2KMT2ASMN1; SMN2
SCHEMBL9818504 0.71

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 28 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0142104-B1 FIBRE-REACTIVE CHROMIUM COMPLEXES, THEIR PREPARATION AND THEIR USE CIBA-GEIGY AG (CH) 1990-01-03 EP claimed
EP-0142104-A2 Fibre-reactive chromium complexes, their preparation and their use CIBA-GEIGY AG (CH) 1985-05-22 EP claimed
US-6066756-A FUNGICIDES, PESTICIDES BASF AKTIENGESELLSCHAFT (DE) 2000-05-23 US disclosed
US-5981581-A FOR CONTROLLING ANIMAL PESTS OR HARMFUL FUNGI BASF AKTIENGESELLSCHAFT (DE) 1999-11-09 US disclosed
US-5977399-A Iminooxymethyleneanilides, preparation thereof and intermediates therefor, and compositions containing them BASF AKTIENGESELLSCHAFT (DE) 1999-11-02 US disclosed
US-5965587-A PESTICIDES, FUNGICIDES BASF AKTIENGESELLSCHAFT (DE) 1999-10-12 US disclosed
US-5931975-A TRIAZINE REACTIVE DYES CIBA SPECIALTY CHEMICALS CORPORATION (US) 1999-08-03 US disclosed
US-5679115-A APPLYING DYE TO FIBER WITH COLORLESS MATERIAL CONTAINING POLYMERIZABLE DOUBLE BOND, FIXING BY TREATING WITH IONIZING RADIATION CIBA-GEIGY CORPORATION (US) 1997-10-21 US disclosed
EP-0681623-B1 RADIATION-INDUCED FIXATION OF DYES CIBA GEIGY (CH) 1997-05-21 EP disclosed
EP-0485336-B1 Mixtures of reactive dyes, process for their preparation and their utilization CIBA GEIGY AG (CH) 1997-03-26 EP disclosed
EP-0629249-B1 PROCESS FOR THE DYEING OF CELLULOSE-CONTAINING FIBRE MATERIALS WITH REACTIVE DYES CIBA GEIGY AG (CH) 1997-01-08 EP disclosed
EP-0201026-B1 METAL COMPLEX DYES BAYER AG (DE) 1989-09-13 EP disclosed
US-4813972-A USING LEVELING DYES, COLORFASTNESS CIBA-GEIGY CORPORATION (US) 1989-03-21 US disclosed
US-4723001-A Fibre-reactive chromium complexes and their preparation and use CIBA-GEIGY CORPORATION (US) 1988-02-02 US disclosed
US-4678851-A FIBER-RACTIVE CIBA-GEIGY CORPORATION (US) 1987-07-07 US disclosed
US-4638054-A Aminonaphthol bisazo reactive dyes BAYER AKTIENGESELLSCHAFT (DE) 1987-01-20 US disclosed
US-4556707-A DYEING CELLULOSE FIBERS AND POLYAMIDE FIBERS BAYER AKTIENGESELLSCHAFT (DE) 1985-12-03 US disclosed
EP-0144776-A2 Fibre-reactive chromium complexes, their preparation and their use CIBA-GEIGY AG (CH) 1985-06-19 EP disclosed
EP-0142104-A2 Fibre-reactive chromium complexes, their preparation and their use CIBA-GEIGY AG (CH) 1985-05-22 EP disclosed
US-4418015-A Phthalocyanine reactive dyestuffs BAYER AKTIENGESELLSCHAFT (DE) 1983-11-29 US disclosed