Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK8 | P45983 | 2/20 | 0.41 |
| ▸ | MAPK9 | P45984 | 2/20 | 0.41 |
| ▸ | MAPK10 | P53779 | 2/20 | 0.41 |
| ▸ | IL2 | P60568 | 1/20 | 0.35 |
| ▸ | MAP4K1 | Q92918 | 1/20 | 0.35 |
| ▸ | ROCK1 | Q13464 | 2/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | ERBB2 | P04626 | 2/20 | 0.33 |
| ▸ | EPHA2 | P29317 | 2/20 | 0.33 |
| ▸ | KDR | P35968 | 2/20 | 0.33 |
| ▸ | EPHB4 | P54760 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1801882 | 0.90 | MAPK8 (0.51) | MAPK8MAPK9MAPK10IL2MAP4K1 | |
| SCHEMBL1801883 | 0.90 | MAPK8 (0.51) | MAPK8MAPK9MAPK10IL2MAP4K1 | |
| SCHEMBL1801448 | 0.89 | MAPK8 (0.48) | MAPK8MAPK9MAPK10IL2MAP4K1 | |
| SCHEMBL8168360 | 0.89 | MAPK8 (0.48) | MAPK8MAPK9MAPK10IL2MAP4K1 | |
| SCHEMBL1801449 | 0.89 | MAPK8 (0.48) | MAPK8MAPK9MAPK10IL2MAP4K1 | |
| SCHEMBL8175210 | 0.87 | MAPK8 (0.59) | MAPK8MAPK9MAPK10IL2MAP4K1 | |
| SCHEMBL1795892 | 0.87 | MAPK8 (0.59) | MAPK8MAPK9MAPK10IL2MAP4K1 | |
| SCHEMBL1795895 | 0.87 | MAPK8 (0.59) | MAPK8MAPK9MAPK10IL2MAP4K1 | |
| SCHEMBL1796697 | 0.87 | IL2 (0.44) | MAPK8MAPK9MAPK10IL2MAP4K1 | |
| SCHEMBL8167255 | 0.85 | MAPK8 (0.62) | MAPK8MAPK9MAPK10IL2MAP4K1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008095943-A1 | THE USE OF 7-AZAINDOLES IN THE INHIBITION OF C-JUN N-TERMINAL KINASE | EISAI R&D MANAGEMENT CO. LTD. (JP) | 2008-08-14 | — | — | WO | disclosed |