Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 5/20 | 0.55 |
| ▸ | OR51E2 | Q9H255 | 1/20 | 0.43 |
| ▸ | THRB | P10828 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | APEX1 | P27695 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.40 |
| ▸ | FKBP5 | Q13451 | 1/20 | 0.38 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | NAAA | Q02083 | 2/20 | 0.35 |
| ▸ | ATM | Q13315 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.33 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.33 |
| ▸ | SIRT3 | Q9NTG7 | 1/20 | 0.33 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| 2-Pyrrolidone SCHEMBL14782269 | 0.96 | TSHR (0.63) | TSHROR51E2THRBTDP1POLB | |
| 2-Pyrrolidone SCHEMBL28734991 | 0.94 | TSHR (0.65) | TSHROR51E2THRBTDP1POLB | |
| Methacrylic Acid SCHEMBL4962568 | 0.91 | TSHR (0.60) | TSHROR51E2THRBTDP1POLB | |
| 2-Pyrrolidone SCHEMBL7522500 | 0.88 | TSHR (0.53) | TSHROR51E2THRBTDP1POLB | |
| 2-Pyrrolidone SCHEMBL15820361 | 0.88 | TSHR (0.53) | TSHROR51E2THRBTDP1POLB | |
| 2-Pyrrolidone SCHEMBL8133376 | 0.87 | OR51E2 (0.47) | TSHROR51E2THRBTDP1POLB | |
| 2-Pyrrolidone SCHEMBL17241782 | 0.85 | OR51E2 (0.46) | TSHROR51E2THRBTDP1POLB | |
| 2-Pyrrolidone SCHEMBL28304483 | 0.85 | OR51E2 (0.46) | TSHROR51E2THRBTDP1POLB | |
| 2-Pyrrolidone SCHEMBL11305029 | 0.84 | TSHR (0.42) | TSHROR51E2THRBHPGDSIRT2 | |
| Methacrylic Acid SCHEMBL28736810 | 0.83 | OR51E2 (0.43) | TSHROR51E2THRBTDP1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106590835-B | A kind of preparation method for the pour depressant for lubricating oil that methanol engine uses | 泰州龙谷信息科技有限公司 | 2019-07-05 | — | — | CN | claimed |
| US-6086547-A | Wire for medical use coated with polyether sulphone and a copolymer | BELDEN WIRE AND CABLE B.V. (NL) | 2000-07-11 | — | — | US | disclosed |