SCHEMBL816913

SCHEMBL816913

C=CC(=O)OCCCCCCOC(=O)Oc1ccc(C(=O)Oc2ccc(OC(=O)c3ccc(OC(=O)OCCCCCCOC(=O)C=C)cc3)cc2)cc1

nearest known ligand 0.53

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TSHR P16473 2/20 0.53
ALDH1A1 P00352 2/20 0.53
CYP3A4 P08684 2/20 0.53
HPGD P15428 2/20 0.45
MAPT P10636 3/20 0.44
MEN1 O00255 1/20 0.44
KMT2A Q03164 1/20 0.44
HTT P42858 1/20 0.43
THRB P10828 3/20 0.42
NPC1 O15118 2/20 0.42
LMNA P02545 2/20 0.42
NFKB1 P19838 1/20 0.42
NFKB2 Q00653 1/20 0.42
RELA Q04206 1/20 0.42
SMN1; SMN2 Q16637 1/20 0.42
CYP1A2 P05177 1/20 0.40
CYP2D6 P10635 1/20 0.40
CYP2C9 P11712 1/20 0.40
CYP2C19 P33261 1/20 0.40
STS P08842 5/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13109517 1.00 TSHR (0.53) TSHRALDH1A1CYP3A4HPGDMAPT
SCHEMBL13656970 1.00 TSHR (0.53) TSHRALDH1A1CYP3A4HPGDMAPT
SCHEMBL14000690 1.00 TSHR (0.53) TSHRALDH1A1CYP3A4HPGDMAPT
SCHEMBL14000707 1.00 TSHR (0.53) TSHRALDH1A1CYP3A4HPGDMAPT
SCHEMBL14072872 1.00 TSHR (0.53) TSHRALDH1A1CYP3A4HPGDMAPT
SCHEMBL14000687 0.99 TSHR (0.51) TSHRALDH1A1CYP3A4HPGDMAPT
SCHEMBL16885064 0.99 TSHR (0.50) TSHRALDH1A1CYP3A4HPGDMAPT
SCHEMBL14072871 0.99 TSHR (0.50) TSHRALDH1A1CYP3A4HPGDMAPT
SCHEMBL10078016 0.99 TSHR (0.50) TSHRALDH1A1CYP3A4HPGDMAPT
SCHEMBL13917592 0.99 TSHR (0.50) TSHRALDH1A1CYP3A4HPGDMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 68 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20150109564-A1 POLARIZING PLATE WITH AN OPTICAL COMPENSATION LAYER, LIQUID CRYSTAL PANEL, LIQUID CRYSTAL DISPLAY APPARATUS, AND IMAGE DISPLAY APPARATUS USING THE POLARIZING PLATE WITH AN OPTICAL COMPENSATION LAYER NITTO DENKO CORPORATION (JP) 2015-04-23 US disclosed
US-20150109564-A1 POLARIZING PLATE WITH AN OPTICAL COMPENSATION LAYER, LIQUID CRYSTAL PANEL, LIQUID CRYSTAL DISPLAY APPARATUS, AND IMAGE DISPLAY APPARATUS USING THE POLARIZING PLATE WITH AN OPTICAL COMPENSATION LAYER NITTO DENKO CORPORATION (JP) 2015-04-23 US disclosed
US-8663497-B2 Liquid crystal composition comprising polymerizable compound, and liquid crystal display element using said liquid crystal composition ADEKA CORPORATION (JP) 2014-03-04 US disclosed
US-8663497-B2 Liquid crystal composition comprising polymerizable compound, and liquid crystal display element using said liquid crystal composition ADEKA CORPORATION (JP) 2014-03-04 US disclosed
EP-2695930-A1 POLYMERIZABLE LIQUID CRYSTAL COMPOSITION, POLARIZED LIGHT-EMITTING COATING MATERIAL, NOVEL NAPHTHOLACTAM DERIVATIVE, NOVEL COUMARIN DERIVATIVE, NOVEL NILE RED DERIVATIVE, AND NOVEL ANTHRACENE DERIVATIVE Adeka Corporation (JP) 2014-02-12 EP disclosed
US-8480925-B2 Depolarizing film, method for production thereof, optical film, and liquid crystal display NITTO DENKO CORPORATION (JP) 2013-07-09 US disclosed
US-8480925-B2 Depolarizing film, method for production thereof, optical film, and liquid crystal display NITTO DENKO CORPORATION (JP) 2013-07-09 US disclosed
EP-2502973-A1 LIQUID CRYSTAL COMPOSITION COMPRISING POLYMERIZABLE COMPOUND, AND LIQUID CRYSTAL DISPLAY ELEMENT USING SAID LIQUID CRYSTAL COMPOSITION Adeka Corporation (JP) 2012-09-26 EP disclosed
US-20120200794-A1 LIQUID CRYSTAL COMPOSITION COMPRISING POLYMERIZABLE COMPOUND, AND LIQUID CRYSTAL DISPLAY ELEMENT USING SAID LIQUID CRYSTAL COMPOSITION ADEKA CORPORATION (JP) 2012-08-09 US disclosed
US-20120200794-A1 LIQUID CRYSTAL COMPOSITION COMPRISING POLYMERIZABLE COMPOUND, AND LIQUID CRYSTAL DISPLAY ELEMENT USING SAID LIQUID CRYSTAL COMPOSITION ADEKA CORPORATION (JP) 2012-08-09 US disclosed
US-20080049179-A1 POLARIZING PLATE WITH OPTICAL COMPENSATION LAYER, METHOD OF PRODUCING THE SAME, AND LIQUID CRYSTAL PANEL, LIQUID CRYSTAL DISPLAY, AND IMAGE DISPLAY INCLUDING THE SAME NITTO DENKO CORPORATION (JP) 2008-02-28 US disclosed
US-20080049179-A1 POLARIZING PLATE WITH OPTICAL COMPENSATION LAYER, METHOD OF PRODUCING THE SAME, AND LIQUID CRYSTAL PANEL, LIQUID CRYSTAL DISPLAY, AND IMAGE DISPLAY INCLUDING THE SAME NITTO DENKO CORPORATION (JP) 2008-02-28 US disclosed
US-7270855-B2 Optical film, method for manufacturing the same, and phase difference film and polarizing plate using the same NITTO DENKO CORPORATION (JP) 2007-09-18 US disclosed
US-7270855-B2 Optical film, method for manufacturing the same, and phase difference film and polarizing plate using the same NITTO DENKO CORPORATION (JP) 2007-09-18 US disclosed
US-20070200976-A1 Elliptically Polarizing Plate, Method Of Producing The Same, And Image Display Apparatus Employing The Elliptically Polarizing Plate NITTO DENKO CORPORATION (JP) 2007-08-30 US disclosed
US-20070200976-A1 Elliptically Polarizing Plate, Method Of Producing The Same, And Image Display Apparatus Employing The Elliptically Polarizing Plate NITTO DENKO CORPORATION (JP) 2007-08-30 US disclosed
US-7235283-B2 Optical compensation plate and deflecting plate using the same NITTO DENKO CORPORATION (JP) 2007-06-26 US disclosed
US-7235283-B2 Optical compensation plate and deflecting plate using the same NITTO DENKO CORPORATION (JP) 2007-06-26 US disclosed
US-20070139773-A1 Method of producing elliptically polarizing plate and image display using the elliptically polarizing plate NITTO DENKO CORPORATION (JP) 2007-06-21 US disclosed
US-20070139773-A1 Method of producing elliptically polarizing plate and image display using the elliptically polarizing plate NITTO DENKO CORPORATION (JP) 2007-06-21 US disclosed