SCHEMBL8169138

SCHEMBL8169138

Cc1cc(C(=O)Nc2ccc(-c3ccccc3S(N)(=O)=O)cc2)n(-c2cc3ccccc3cc2S(C)(=O)=O)n1

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
F10 P00742 20/20 1.00

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8163927 0.96 F10 (0.93) F10
SCHEMBL8163861 0.95 F10 (1.00) F10
SCHEMBL4362454 0.94 F10 (0.90) F10
SCHEMBL8162846 0.91 F10 (0.88) F10
SCHEMBL8169904 0.91 F10 (0.84) F10
SCHEMBL8168536 0.90 F10 (1.00) F10
SCHEMBL8162841 0.90 F10 (1.00) F10
SCHEMBL8164292 0.89 F10 (0.85) F10
SCHEMBL8163052 0.89 F10 (1.00) F10
SCHEMBL8156863 0.89 F10 (1.00) F10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20040116399-A1 Inhibitors of factor Xa MILLENNIUM PHARMACEUTICALS, INC. 2004-06-17 US disclosed