Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DNTT | P04053 | 1/20 | 0.62 |
| ▸ | BACE1 | P56817 | 1/20 | 0.59 |
| ▸ | POLB | P06746 | 2/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.55 |
| ▸ | HTT | P42858 | 4/20 | 0.55 |
| ▸ | MEN1 | O00255 | 4/20 | 0.55 |
| ▸ | MAPT | P10636 | 4/20 | 0.55 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.55 |
| ▸ | HSP90AA1 | P07900 | 2/20 | 0.55 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.55 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.55 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.55 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.55 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.55 |
| ▸ | ATM | Q13315 | 1/20 | 0.55 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.52 |
| ▸ | SNCA | P37840 | 4/20 | 0.51 |
| ▸ | APP | P05067 | 3/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8169410 | 1.00 | DNTT (0.62) | DNTTBACE1POLBALDH1A1KMT2A | |
| SCHEMBL5038610 | 0.92 | BACE1 (0.67) | DNTTBACE1POLBALDH1A1KMT2A | |
| SCHEMBL5038607 | 0.92 | BACE1 (0.67) | DNTTBACE1POLBALDH1A1KMT2A | |
| SCHEMBL8168163 | 0.85 | DNTT (0.54) | DNTTBACE1POLBALDH1A1KMT2A | |
| SCHEMBL8168162 | 0.85 | DNTT (0.54) | DNTTBACE1POLBALDH1A1KMT2A | |
| SCHEMBL10624957 | 0.83 | SNCA (0.62) | DNTTBACE1POLBALDH1A1KMT2A | |
| SCHEMBL10624962 | 0.83 | SNCA (0.62) | DNTTBACE1POLBALDH1A1KMT2A | |
| SCHEMBL3220639 | 0.82 | BACE1 (0.81) | DNTTBACE1POLBALDH1A1KMT2A | |
| SCHEMBL3220655 | 0.82 | BACE1 (0.81) | DNTTBACE1POLBALDH1A1KMT2A | |
| SCHEMBL15486131 | 0.81 | MEN1 (0.61) | DNTTBACE1POLBALDH1A1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6043247-A | A SUBSTITUTED ACRYLIC ACIDS FOR USE IN TREATMENT OF HUMAN AND ANIMAL DISORDERS, AND PURIFICATION OF PROTEINS OR GLYCOPROTEINS, AND TO THEIR USE IN DIAGNOSIS | NOVO NORDISK A/S (DK) | 2000-03-28 | — | — | US | claimed |
| WO-1997039748-A1 | MODULATORS OF MOLECULES WITH PHOSPHOTYROSINE RECOGNITION UNITS | NOVO NORDISK A/S (DK) | 1997-10-30 | — | — | WO | claimed |
| US-6043247-A | A SUBSTITUTED ACRYLIC ACIDS FOR USE IN TREATMENT OF HUMAN AND ANIMAL DISORDERS, AND PURIFICATION OF PROTEINS OR GLYCOPROTEINS, AND TO THEIR USE IN DIAGNOSIS | NOVO NORDISK A/S (DK) | 2000-03-28 | — | — | US | disclosed |