Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACE | P12821 | 6/20 | 0.48 |
| ▸ | REN | P00797 | 4/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.48 |
| ▸ | F2 | P00734 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | LTA4H | P09960 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 1/20 | 0.48 |
| ▸ | PEPD | P12955 | 1/20 | 0.48 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.48 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.48 |
| ▸ | HTR2A | P28223 | 1/20 | 0.48 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.48 |
| ▸ | HRH1 | P35367 | 1/20 | 0.48 |
| ▸ | THPO | P40225 | 1/20 | 0.48 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.48 |
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | CMA1 | P23946 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8169782 | 0.89 | DPP4 (0.43) | PEPDDPP4DPP8DPP9ELANE | |
| SCHEMBL8161391 | 0.89 | ELANE (0.43) | CMA1DPP4DPP8DPP9ELANE | |
| SCHEMBL239406 | 0.87 | ACE (0.52) | ACERENKDM4EF2LMNA | |
| SCHEMBL242197 | 0.87 | ACE (0.52) | ACERENKDM4EF2LMNA | |
| SCHEMBL12598148 | 0.87 | ACE (0.52) | ACERENKDM4EF2LMNA | |
| SCHEMBL12567110 | 0.87 | ACE (0.52) | ACERENKDM4EF2LMNA | |
| SCHEMBL239407 | 0.87 | ACE (0.52) | ACERENKDM4EF2LMNA | |
| SCHEMBL15692916 | 0.86 | ACE (0.48) | ACERENKDM4EF2LMNA | |
| SCHEMBL8273010 | 0.84 | ACE (0.44) | ACERENKDM4EF2LMNA | |
| SCHEMBL2162326 | 0.82 | CMA1 (0.61) | ACERENCMA1ELANE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008095058-A1 | HCV PROTEASE INHIBITORS | TAIGEN BIOTECHNOLOGY CO. LTD. (TW) | 2008-08-07 | — | — | WO | disclosed |