Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 15/20 | 0.50 |
| ▸ | MEN1 | O00255 | 11/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 11/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 6/20 | 0.47 |
| ▸ | NPC1 | O15118 | 5/20 | 0.47 |
| ▸ | RAB9A | P51151 | 5/20 | 0.47 |
| ▸ | GAA | P10253 | 4/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 6/20 | 0.43 |
| ▸ | ALOX12 | P18054 | 3/20 | 0.43 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 3/20 | 0.40 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.40 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.40 |
| ▸ | RELA | Q04206 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8170287 | 1.00 | MAPT (0.50) | MAPTMEN1KMT2ATDP1ALDH1A1 | |
| SCHEMBL14675630 | 0.87 | MAPT (0.53) | MAPTMEN1KMT2ATDP1ALDH1A1 | |
| SCHEMBL30769484 | 0.85 | MAPT (0.61) | MAPTMEN1KMT2ATDP1ALDH1A1 | |
| SCHEMBL942294 | 0.85 | MAPT (0.61) | MAPTMEN1KMT2ATDP1ALDH1A1 | |
| SCHEMBL942292 | 0.85 | MAPT (0.61) | MAPTMEN1KMT2ATDP1ALDH1A1 | |
| SCHEMBL10893010 | 0.85 | MAPT (0.46) | MAPTMEN1KMT2ATDP1ALDH1A1 | |
| SCHEMBL10704830 | 0.79 | MAPT (0.57) | MAPTMEN1KMT2ATDP1ALDH1A1 | |
| SCHEMBL10899990 | 0.79 | MAPT (0.58) | MAPTMEN1KMT2ATDP1ALDH1A1 | |
| SCHEMBL10899994 | 0.79 | MAPT (0.58) | MAPTMEN1KMT2ATDP1ALDH1A1 | |
| SCHEMBL10704824 | 0.79 | MAPT (0.57) | MAPTMEN1KMT2ATDP1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6156466-A | Photoconductor for electrophotography | FUJI ELECTRIC CO., LTD. (JP) | 2000-12-05 | — | — | US | disclosed |
| US-5460907-A | Polymer, optical chromophore, charge transport agent; diffraction efficiency; waveguides | INTERNATIONAL BUSINESS MACHINES CORPORATION (US) | 1995-10-24 | — | — | US | disclosed |
| EP-0482779-A2 | Photorefractive material | International Business Machines Corporation (US) | 1992-04-29 | — | — | EP | disclosed |
| US-5064264-A | Optical waveguides | INTERNATIONAL BUSINESS MACHINES CORPORATION (US) | 1991-11-12 | — | — | US | disclosed |