SCHEMBL8171237

SCHEMBL8171237

Cc1cc(C(=O)Nc2ccc(C(=N)N3CCC3)cc2F)n(-c2cc3ccccc3cc2F)n1

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
F10 P00742 20/20 1.00

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8164238 0.98 F10 (1.00) F10
SCHEMBL8167946 0.97 F10 (1.00) F10
SCHEMBL8162963 0.97 F10 (1.00) F10
SCHEMBL8162978 0.92 F10 (1.00) F10
SCHEMBL8407361 0.91 F10 (0.84) F10
SCHEMBL8170323 0.90 F10 (0.81) F10
SCHEMBL8170853 0.89 F10 (0.80) F10
SCHEMBL8158796 0.89 F10 (0.80) F10
SCHEMBL8157116 0.89 F10 (1.00) F10
SCHEMBL8168527 0.88 F10 (1.00) F10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20040116399-A1 Inhibitors of factor Xa MILLENNIUM PHARMACEUTICALS, INC. 2004-06-17 US disclosed
US-20040116399-A1 Inhibitors of factor Xa MILLENNIUM PHARMACEUTICALS, INC. 2004-06-17 US disclosed