Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GBA1 | P04062 | 4/20 | 0.88 |
| ▸ | GANAB | Q14697 | 2/20 | 0.88 |
| ▸ | GLB1 | P16278 | 1/20 | 0.45 |
| ▸ | FUCA1 | P04066 | 4/20 | 0.43 |
| ▸ | FUCA2 | Q9BTY2 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 2/20 | 0.40 |
| ▸ | MGAM | O43451 | 1/20 | 0.40 |
| ▸ | PYGL | P06737 | 1/20 | 0.40 |
| ▸ | AGL | P35573 | 1/20 | 0.40 |
| ▸ | SI | P14410 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8170898 | 1.00 | GBA1 (0.88) | GBA1GANABGLB1FUCA1FUCA2 | |
| SCHEMBL8171977 | 1.00 | GBA1 (0.88) | GBA1GANABGLB1FUCA1FUCA2 | |
| SCHEMBL8170837 | 1.00 | GBA1 (0.88) | GBA1GANABGLB1FUCA1FUCA2 | |
| SCHEMBL8170879 | 1.00 | GBA1 (0.88) | GBA1GANABGLB1FUCA1FUCA2 | |
| SCHEMBL8172702 | 1.00 | GBA1 (0.88) | GBA1GANABGLB1FUCA1FUCA2 | |
| SCHEMBL11193060 | 0.94 | GBA1 (1.00) | GBA1GANABGLB1FUCA1FUCA2 | |
| SCHEMBL11193067 | 0.94 | GBA1 (1.00) | GBA1GANABGLB1FUCA1FUCA2 | |
| SCHEMBL8170745 | 0.83 | GBA1 (0.62) | GBA1GANABGLB1GAA | |
| SCHEMBL8178036 | 0.83 | GBA1 (0.62) | GBA1GANABGLB1GAA | |
| SCHEMBL8178736 | 0.83 | GBA1 (0.62) | GBA1GANABGLB1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0973738-A1 | NOVEL HETEROCYCLIC COMPOUNDS | NOVO NORDISK A/S (DK) | 2000-01-26 | — | — | EP | claimed |
| WO-1998040353-A1 | NOVEL HETEROCYCLIC COMPOUNDS | NOVO NORDISK A/S (DK) | 1998-09-17 | — | — | WO | claimed |
| EP-0973738-A1 | NOVEL HETEROCYCLIC COMPOUNDS | NOVO NORDISK A/S (DK) | 2000-01-26 | — | — | EP | disclosed |
| US-5952363-A | Pyrrolidine compounds useful in the treatment of diabetes | NOVO NORDISK A/S (DK) | 1999-09-14 | — | — | US | disclosed |
| WO-1998040353-A1 | NOVEL HETEROCYCLIC COMPOUNDS | NOVO NORDISK A/S (DK) | 1998-09-17 | — | — | WO | disclosed |