Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2C | P28335 | 5/20 | 0.45 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.39 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.39 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.39 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.39 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.39 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL817794 | 0.91 | HTR2A (0.43) | HTR2CCYP2D6SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL817421 | 0.90 | HTR2C (0.56) | HTR2CSLC6A2SLC6A4SLC6A3 | |
| SCHEMBL10405257 | 0.87 | HTR2C (0.44) | HTR2CCYP2D6SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL817651 | 0.86 | HTR2C (0.50) | HTR2C | |
| SCHEMBL817590 | 0.83 | HTR2C (0.37) | HTR2CSLC6A2SLC6A4SLC6A3 | |
| SCHEMBL4213803 | 0.79 | JAK3 (0.49) | HTR2CCYP2D6SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL1663055 | 0.79 | JAK3 (0.49) | HTR2CCYP2D6SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL30776200 | 0.79 | JAK3 (0.49) | HTR2CCYP2D6SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL818680 | 0.78 | HTR2C (0.41) | HTR2C | |
| SCHEMBL5968190 | 0.77 | PARP1 (0.54) | CYP2D6SLC6A2SLC6A4SLC6A3KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110275756-A1 | CONJUGATED DIENE POLYMER, CONJUGATED DIENE POLYMER COMPOSITION, AND METHOD FOR PRODUCING CONJUGATED DIENE POLYMER | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2011-11-10 | — | — | US | disclosed |